Results 1 to 10 of about 9,955 (227)

Oxalate Nephropathy in a Patient With Chronic Pancreatitis and Recent Surgery: A Clinical Conundrum [PDF]

Kidney Medicine
Calcium oxalate nephropathy is a rare condition with both primary and secondary causes. Primary hyperoxaluria, an inherited disorder, leads to liver oxalate overproduction, whereas secondary hyperoxaluria, or enteric hyperoxaluria, may be multifactorial ...
Robert Seby, Krista Grennan, Jacob Henderson, Cene Ovincy, Fadi Salem, John Lieske, Ivan Porter, LaTonya Hickson   +7 more
doaj   +2 more sources

Hyperoxaluria by the AGXT gene: a case report [PDF]

Journal of Medical Case Reports
Background This report details a case of AGXT gene mutation in a male patient, 9 years 6 months old, Portuguese ethnicity, with history of nephrocalcinosis and recurrent nephrolithiasis in childhood, which progressed to chronic kidney disease.
Alessandra Vitorino Naghettini, Alice Leite Mesquita, Andrielle Nunes Santos, Juliana Vieira Peixoto Moreira, Maysa Campos Mota de Oliveira, Patrícia Marques Fortes   +5 more
doaj   +2 more sources

Hydrogen Sulfide Deficiency Contributes to Tubular Damage and Calcium Oxalate Crystal Formation in Hyperoxaluria Nephropathy: Role of Osteopontin and Tamm–Horsfall Protein [PDF]

Antioxidants
Hydrogen sulfide (H2S) exerts regulatory functions in kidney diseases. However, its protective role against kidney stone formation remains unclear. Here, we demonstrate that hyperoxaluria or oxalate exposure impairs H2S formation, leading to tubular ...
Chien-Lin Lu, Yi-Shiou Tseng, Wen-Bin Wu, Chun-Hou Liao, Ming-Chieh Ma   +4 more
doaj   +2 more sources

The domestic pig as a translational model of hyperoxaluria: a pilot study of acute and chronic sodium oxalate infusion [PDF]

Frontiers in Physiology
The purpose of this pilot study was to develop and characterize an in vivo porcine model of hyperoxaluria using intravenous infusion of sodium oxalate (NaOx). Two experimental regimens were developed to replicate acute and follow up chronic hyperoxaluria.
Tomasz Jacek, Dominika Szkopek, Piotr Wychowański, Piotr Wychowański, Janine Donaldson, Kamil Zaworski, Mariusz Strutyński, Siarhei Kirko, Olena Prykhodko, Olena Prykhodko, Olexandr Fedkiv, Olexandr Fedkiv, Stefan G. Pierzynowski, Stefan G. Pierzynowski, Stefan G. Pierzynowski, Kateryna Pierzynowska, Kateryna Pierzynowska, Kateryna Pierzynowska   +17 more
doaj   +2 more sources

Gut microbiota modulation via fecal microbiota transplantation mitigates hyperoxaluria and calcium oxalate crystal depositions induced by high oxalate diet

Gut Microbes
Hyperoxaluria, including primary and secondary hyperoxaluria, is a disorder characterized by increased urinary oxalate excretion and could lead to recurrent calcium oxalate kidney stones, nephrocalcinosis and eventually end stage renal disease.
Lingyue An, Shujue Li, Zhenglin Chang, Min Lei, Zhican He, Peng Xu, Shike Zhang, Zheng Jiang, Muhammad Sarfaraz Iqbal, Xinyuan Sun, Hongxing Liu, Xiaolu Duan, Wenqi Wu   +12 more
exaly   +3 more sources

Delta weight loss unlike genetic variation associates with hyperoxaluria after malabsorptive bariatric surgery

Scientific Reports, 2023
The risk of enteric hyperoxaluria is significantly increased after malabsorptive bariatric surgery (MBS). However, its underlying determinants are only poorly characterized. In this case–control study, we aimed at identifying clinical and genetic factors
Lotte Scherer, Ria Schönauer, Melanie Nemitz-Kliemchen, Tobias Hagemann, Elena Hantmann, Jonathan de Fallois, Friederike Petzold, Matthias Blüher, Jan Halbritter   +8 more
doaj   +1 more source

The Primary Hyperoxalurias [PDF]

Journal of the American Society of Nephrology, 2001
The primary hyperoxalurias (PHs) are rare disorders of glyoxylate metabolism in which specific hepatic enzyme deficiencies result in overproduction of oxalate. Due to the resulting severe hyperoxaluria, recurrent urolithiasis or progressive nephrocalcinosis are principal manifestations.
Marangella, M, PETRARULO, MICHELE, Vitale, C, Bagnis, C, Berutti, S, Ramello, A, Amoroso, A   +6 more
openaire   +5 more sources

Frequency and impact of enteric hyperoxaluria in pediatric short bowel syndrome: a retrospective single centre study

Frontiers in Pediatrics, 2023
ObjectivesThe survival of pediatric patients with short bowel syndrome has improved in recent years. Enteric hyperoxaluria as a pathophysiological consequence has been hardly addressed so far.
Jan Thomas Schaefer, Jan Thomas Schaefer, Susanne Schulz-Heise, Aline Rueckel, Manfred Rauh, Joerg Juengert, Matthias Galiano, Norbert Meier, Joachim Woelfle, Mario Schiffer, André Hoerning   +10 more
doaj   +1 more source

Lanthanum carbonate to control plasma and urinary oxalate level in type 1 primary hyperoxaluria?

IJU Case Reports, 2021
Introduction The therapy to reduce urinary oxalate excretion in primary hyperoxaluria type 1 is still required. Case presentation A 37‐year‐old hemodialyzed man suffered from systemic oxalosis secondary to primary hyperoxaluria type 1 exhibited a drastic
Agnieszka Pozdzik, Cristina David, Jelle Vekeman, Frederik Tielens, Michel Daudon   +4 more
doaj   +1 more source

Homozygous GRHPR C.494G>A mutation is deleterious that causes early onset of nephrolithiasis in West Bengal, India

Frontiers in Molecular Biosciences, 2022
Pediatric nephrolithiasis (NL) or Kidney stone disease (KSD) is an untethered topic in Asian population. In Western countries, the annual incidence of paediatric NL is around 6–10%.
Arindam Chatterjee, Kunal Sarkar, Sarbashri Bank, Sudakshina Ghosh, Dilip Kumar Pal, Siddharth Saraf, Dhansagar Wakle, Bidyut Roy, Santanu Chakraborty, Biswabandhu Bankura, Biswabandhu Bankura, Debprasad Chattopadhyay, Debprasad Chattopadhyay, Debprasad Chattopadhyay, Madhusudan Das   +14 more
doaj   +1 more source