Results 21 to 30 of about 5,140 (180)

In Vitro Cell Culture Models of Hyperoxaluric States: Calcium Oxalate and Renal Epithelial Cell Interactions

Crystals, 2021
Urolithiasis is a multifactorial disease with a high incidence and high recurrence rate, characterized by formation of solid deposits in the urinary tract. The most common type of these stones are calcium oxalate stones.
Ana Petrović, Tomislav Kizivat, Ines Bilić Ćurčić, Robert Smolić, Martina Smolić   +4 more
doaj   +1 more source

Probiotics in urolithiasis

Journal of Education, Health and Sport, 2018
Urolithiasis is considered a civilization disease. The prevalence is estimated at 5-20% of the population. There are many litogenesis risk factors such as hypercalciuria, hypophosphaturia, low urine pH or increased excretion of oxalates with urine - a ...
Monika Kusz, Adam Alzubedi, Joanna Popiołek, Michał Konopelko   +3 more
doaj   +3 more sources

Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition. [PDF]

PLoS ONE, 2017
Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes renal injury and inflammation leading to number of diseases including chronic kidney disease (CKD).
Sunil Joshi, Wei Wang, Saeed R Khan
doaj   +1 more source

Oxalate Homeostasis in Non-Stone-Forming Chronic Kidney Disease: A Review of Key Findings and Perspectives

Biomedicines, 2023
Chronic kidney disease (CKD) is a significant global public health concern associated with high morbidity and mortality rates. The maintenance of oxalate homeostasis plays a critical role in preserving kidney health, particularly in the context of CKD ...
Natalia Stepanova
doaj   +1 more source

Isolated Kidney Transplant in Primary Hyperoxaluria-1 Enabled by Small Interfering RNA (siRNA) Therapy. Is It Time for Change? Case Report and Review of the Literature. [PDF]

Pediatr Transplant
ABSTRACT Background Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by excessive oxalate production that leads to nephrocalcinosis or nephrolithiasis and progressive kidney failure, associated with systemic oxalosis that is not reversed by dialysis. Pharmacological treatment is limited.
Habeeb SM, Simkova E, Al-Akash S, Awad HS, Yamin H, Eid LA, Aldhaheri WS, Concepcion W, Bitzan M.   +8 more
europepmc   +2 more sources

Vitamin C-Induced Oxalate Nephropathy

International Journal of Nephrology, 2011
Although a multitude of syndromes have been thoroughly described as a result of vitamin deficiencies, over consumption of such substances may also be quite dangerous.
Jorge Lamarche, Reji Nair, Alfredo Peguero, Craig Courville   +3 more
doaj   +1 more source

Secondary oxalate nephropathy and impact of high‐dose vitamin C intake for COVID‐19 prevention on a patient with Roux‐en‐Y gastric bypass: A case report

Clinical Case Reports, 2023
The current study is important in informing clinicians about the possibility of concurrent oxalate nephropathy caused by Roux‐en‐Y gastric bypass, high oxalate materials, and high‐dose vitamin C intake for COVID‐19 prevention.
Fatemeh Kafi, Mojgan Mortazavi, Alireza Pouramini, Shahaboddin Dolatkhah, Behrouz Kaleidari, Diana Taheri   +5 more
doaj   +1 more source

Oxalate as a potent promoter of kidney stone formation

Frontiers in Medicine, 2023
Kidney stones are among the most prevalent urological diseases, with a high incidence and recurrence rate. Treating kidney stones has been greatly improved by the development of various minimally invasive techniques.
Tao Chen, Tao Chen, Tao Chen, Biao Qian, Biao Qian, Junrong Zou, Junrong Zou, Peiyue Luo, Peiyue Luo, Peiyue Luo, Jun Zou, Jun Zou, Jun Zou, Wei Li, Wei Li, Wei Li, Qi Chen, Qi Chen, Qi Chen, Liying Zheng   +19 more
doaj   +1 more source

Protective effects of ethanolic extract of Cuscuta reflexa Roxb. against ethylene glycol-induced hyperoxaluria and urolithiasis in rats [PDF]

Journal of HerbMed Pharmacology
Introduction: Renal urolithiasis is a prevalent global health concern due to its high recurrence rate. Cuscuta reflexa (Roxb) has been traditionally used for its anti-inflammatory and antioxidant properties.
Madan L. Kaushik, Nishant Goutam, Mahendra Singh Ashawat   +2 more
doaj   +1 more source

Gut microbiota modulation via fecal microbiota transplantation mitigates hyperoxaluria and calcium oxalate crystal depositions induced by high oxalate diet

Gut Microbes
Hyperoxaluria, including primary and secondary hyperoxaluria, is a disorder characterized by increased urinary oxalate excretion and could lead to recurrent calcium oxalate kidney stones, nephrocalcinosis and eventually end stage renal disease.
Lingyue An, Shujue Li, Zhenglin Chang, Min Lei, Zhican He, Peng Xu, Shike Zhang, Zheng Jiang, Muhammad Sarfaraz Iqbal, Xinyuan Sun, Hongxing Liu, Xiaolu Duan, Wenqi Wu   +12 more
doaj   +1 more source