Results 21 to 30 of about 7,435 (215)

The primary hyperoxalurias [PDF]

Kidney International, 2009
The primary hyperoxalurias (PHs) are rare disorders of glyoxylate metabolism in which specific hepatic enzyme deficiencies result in overproduction of oxalate. Due to the resulting severe hyperoxaluria, recurrent urolithiasis or progressive nephrocalcinosis are principal manifestations.
Hoppe, Bernd, Beck, Bodo B., Milliner, Dawn S.   +2 more
openaire   +2 more sources

Purslane-induced oxalate nephropathy: case report and literature review

BMC Nephrology, 2023
Background The kidney is particularly vulnerable to toxins due to its abundant blood supply, active tubular reabsorption, and medullary interstitial concentration.
Xiangtuo Wang, Xiaoyan Zhang, Liyuan Wang, Ruiying Zhang, Yingxuan Zhang, Lei Cao   +5 more
doaj   +1 more source

Deleterious AGXT Missense Variant Associated with Type 1 Primary Hyperoxaluria (PH1) in Zwartbles Sheep. [PDF]

, 2020
Severe oxalate nephropathy has been previously reported in sheep and is mostly associated with excessive oxalate in the diet. However, a rare native Dutch breed (Zwartbles) seems to be predisposed to an inherited juvenile form of primary hyperoxaluria ...
Orr, Hannah, Strugnell, Ben, Henderson, Katrina, Paris, Julia M., Scholes, Sandra, Cord Drögemüller, Ben Strugnell, Häfliger, Irene M., Katrina Henderson, Geraghty, Tim, Sandra Scholes, Reinie Dijkman, Drögemüller, Cord, Tim Geraghty, Dijkman, Reinie, Letko, Anna, Irene M. Häfliger, Anna Letko, Julia M. Paris, Hannah Orr   +19 more
core   +2 more sources

Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II [PDF]

, 2002
Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II.BackgroundHyperoxaluria may be idiopathic, secondary, or due to primary hyperoxaluria (PH).
Milliner, Dawn S., Monico, Carla G., Ford, G. Charles, Rumsby, Gill, Carla G. Monico, Persson, Mai, Mai Persson, Gill Rumsby, Dawn S. Milliner, G. Charles Ford   +9 more
core   +1 more source

Primary hyperoxaluria: the pediatric nephrologist's point of view

, 2022
The clinical presentation of primary hyperoxaluria in children ranges from mildly symptomatic nephrocalcinosis to very early onset end-stage kidney failure with systemic oxalosis, a devastating complication.
Garrelfs, Sander F, Groothoff, Jaap W, Ben-Shalom, Efrat, Groothoff, Jaap W., Garrelfs, Sander F.   +4 more
core   +1 more source

In Vitro Cell Culture Models of Hyperoxaluric States: Calcium Oxalate and Renal Epithelial Cell Interactions

Crystals, 2021
Urolithiasis is a multifactorial disease with a high incidence and high recurrence rate, characterized by formation of solid deposits in the urinary tract. The most common type of these stones are calcium oxalate stones.
Ana Petrović, Tomislav Kizivat, Ines Bilić Ćurčić, Robert Smolić, Martina Smolić   +4 more
doaj   +1 more source

Pyridoxamine lowers kidney crystals in experimental hyperoxaluria: A potential therapy for primary hyperoxaluria [PDF]

, 2005
Pyridoxamine lowers kidney crystals in experimental hyperoxaluria: A potential therapy for primary hyperoxaluria.BackgroundPrimary hyperoxaluria is a rare genetic disorder of glyoxylate metabolism that results in overproduction of oxalate. The disease is
Kim, Daniel, Hudson, Billy G., Belmont, John M., Sergei V. Chetyrkin, Daniel Kim, Chetyrkin, Sergei V., Paul A. Voziyan, Scheinman, J.O.N. I., Voziyan, Paul A., J.O.N. I. Scheinman, John M. Belmont, Billy G. Hudson   +11 more
core   +1 more source

Hyperoxaluria in children [PDF]

, 2014
Hiperoksalurija je jedan od glavnih rizičnih čimbenika za rekurentnu urolitijazu i progresivnu nefrokalcinozu. Odgovorna je za 2-20% metaboličkih rizičnih faktora identificiranih u djece i adolescenata s urolitijazom.
Barić, Anastasija
core   +1 more source

Probiotics in urolithiasis

Journal of Education, Health and Sport, 2018
Urolithiasis is considered a civilization disease. The prevalence is estimated at 5-20% of the population. There are many litogenesis risk factors such as hypercalciuria, hypophosphaturia, low urine pH or increased excretion of oxalates with urine - a ...
Monika Kusz, Adam Alzubedi, Joanna Popiołek, Michał Konopelko   +3 more
doaj   +3 more sources

Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition. [PDF]

PLoS ONE, 2017
Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes renal injury and inflammation leading to number of diseases including chronic kidney disease (CKD).
Sunil Joshi, Wei Wang, Saeed R Khan
doaj   +1 more source