Results 31 to 40 of about 6,717 (218)
The primary hyperoxalurias [PDF]
The primary hyperoxalurias (PHs) are rare disorders of glyoxylate metabolism in which specific hepatic enzyme deficiencies result in overproduction of oxalate. Due to the resulting severe hyperoxaluria, recurrent urolithiasis or progressive nephrocalcinosis are principal manifestations.
Hoppe, Bernd +2 more
openaire +2 more sources
Deleterious AGXT Missense Variant Associated with Type 1 Primary Hyperoxaluria (PH1) in Zwartbles Sheep. [PDF]
Severe oxalate nephropathy has been previously reported in sheep and is mostly associated with excessive oxalate in the diet. However, a rare native Dutch breed (Zwartbles) seems to be predisposed to an inherited juvenile form of primary hyperoxaluria ...
Orr, Hannah +19 more
core +1 more source
Purslane-induced oxalate nephropathy: case report and literature review
Background The kidney is particularly vulnerable to toxins due to its abundant blood supply, active tubular reabsorption, and medullary interstitial concentration.
Xiangtuo Wang +5 more
doaj +1 more source
Primary hyperoxaluria: the pediatric nephrologist's point of view
The clinical presentation of primary hyperoxaluria in children ranges from mildly symptomatic nephrocalcinosis to very early onset end-stage kidney failure with systemic oxalosis, a devastating complication.
Garrelfs, Sander F +4 more
core +1 more source
Urolithiasis is a multifactorial disease with a high incidence and high recurrence rate, characterized by formation of solid deposits in the urinary tract. The most common type of these stones are calcium oxalate stones.
Ana Petrović +4 more
doaj +1 more source
Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition. [PDF]
Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes renal injury and inflammation leading to number of diseases including chronic kidney disease (CKD).
Sunil Joshi, Wei Wang, Saeed R Khan
doaj +1 more source
Urolithiasis is considered a civilization disease. The prevalence is estimated at 5-20% of the population. There are many litogenesis risk factors such as hypercalciuria, hypophosphaturia, low urine pH or increased excretion of oxalates with urine - a ...
Monika Kusz +3 more
doaj +3 more sources
Chronic kidney disease (CKD) is a significant global public health concern associated with high morbidity and mortality rates. The maintenance of oxalate homeostasis plays a critical role in preserving kidney health, particularly in the context of CKD ...
Natalia Stepanova
doaj +1 more source
The current study is important in informing clinicians about the possibility of concurrent oxalate nephropathy caused by Roux‐en‐Y gastric bypass, high oxalate materials, and high‐dose vitamin C intake for COVID‐19 prevention.
Fatemeh Kafi +5 more
doaj +1 more source
Vitamin C-Induced Oxalate Nephropathy
Although a multitude of syndromes have been thoroughly described as a result of vitamin deficiencies, over consumption of such substances may also be quite dangerous.
Jorge Lamarche +3 more
doaj +1 more source

