Results 31 to 40 of about 6,717 (218)

The primary hyperoxalurias [PDF]

open access: yesKidney International, 2009
The primary hyperoxalurias (PHs) are rare disorders of glyoxylate metabolism in which specific hepatic enzyme deficiencies result in overproduction of oxalate. Due to the resulting severe hyperoxaluria, recurrent urolithiasis or progressive nephrocalcinosis are principal manifestations.
Hoppe, Bernd   +2 more
openaire   +2 more sources

Deleterious AGXT Missense Variant Associated with Type 1 Primary Hyperoxaluria (PH1) in Zwartbles Sheep. [PDF]

open access: yes, 2020
Severe oxalate nephropathy has been previously reported in sheep and is mostly associated with excessive oxalate in the diet. However, a rare native Dutch breed (Zwartbles) seems to be predisposed to an inherited juvenile form of primary hyperoxaluria ...
Orr, Hannah   +19 more
core   +1 more source

Purslane-induced oxalate nephropathy: case report and literature review

open access: yesBMC Nephrology, 2023
Background The kidney is particularly vulnerable to toxins due to its abundant blood supply, active tubular reabsorption, and medullary interstitial concentration.
Xiangtuo Wang   +5 more
doaj   +1 more source

Primary hyperoxaluria: the pediatric nephrologist's point of view

open access: yes, 2022
The clinical presentation of primary hyperoxaluria in children ranges from mildly symptomatic nephrocalcinosis to very early onset end-stage kidney failure with systemic oxalosis, a devastating complication.
Garrelfs, Sander F   +4 more
core   +1 more source

In Vitro Cell Culture Models of Hyperoxaluric States: Calcium Oxalate and Renal Epithelial Cell Interactions

open access: yesCrystals, 2021
Urolithiasis is a multifactorial disease with a high incidence and high recurrence rate, characterized by formation of solid deposits in the urinary tract. The most common type of these stones are calcium oxalate stones.
Ana Petrović   +4 more
doaj   +1 more source

Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition. [PDF]

open access: yesPLoS ONE, 2017
Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes renal injury and inflammation leading to number of diseases including chronic kidney disease (CKD).
Sunil Joshi, Wei Wang, Saeed R Khan
doaj   +1 more source

Probiotics in urolithiasis

open access: yesJournal of Education, Health and Sport, 2018
Urolithiasis is considered a civilization disease. The prevalence is estimated at 5-20% of the population. There are many litogenesis risk factors such as hypercalciuria, hypophosphaturia, low urine pH or increased excretion of oxalates with urine - a ...
Monika Kusz   +3 more
doaj   +3 more sources

Oxalate Homeostasis in Non-Stone-Forming Chronic Kidney Disease: A Review of Key Findings and Perspectives

open access: yesBiomedicines, 2023
Chronic kidney disease (CKD) is a significant global public health concern associated with high morbidity and mortality rates. The maintenance of oxalate homeostasis plays a critical role in preserving kidney health, particularly in the context of CKD ...
Natalia Stepanova
doaj   +1 more source

Secondary oxalate nephropathy and impact of high‐dose vitamin C intake for COVID‐19 prevention on a patient with Roux‐en‐Y gastric bypass: A case report

open access: yesClinical Case Reports, 2023
The current study is important in informing clinicians about the possibility of concurrent oxalate nephropathy caused by Roux‐en‐Y gastric bypass, high oxalate materials, and high‐dose vitamin C intake for COVID‐19 prevention.
Fatemeh Kafi   +5 more
doaj   +1 more source

Vitamin C-Induced Oxalate Nephropathy

open access: yesInternational Journal of Nephrology, 2011
Although a multitude of syndromes have been thoroughly described as a result of vitamin deficiencies, over consumption of such substances may also be quite dangerous.
Jorge Lamarche   +3 more
doaj   +1 more source

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