Results 31 to 40 of about 7,435 (215)
Biomedicines, 2023 Chronic kidney disease (CKD) is a significant global public health concern associated with high morbidity and mortality rates. The maintenance of oxalate homeostasis plays a critical role in preserving kidney health, particularly in the context of CKD ...
Natalia Stepanova
doaj +1 more source
Vitamin C-Induced Oxalate Nephropathy
International Journal of Nephrology, 2011 Although a multitude of syndromes have been thoroughly described as a result of vitamin deficiencies, over consumption of such substances may also be quite dangerous.
Jorge Lamarche +3 more
doaj +1 more source
Clinical Case Reports, 2023 The current study is important in informing clinicians about the possibility of concurrent oxalate nephropathy caused by Roux‐en‐Y gastric bypass, high oxalate materials, and high‐dose vitamin C intake for COVID‐19 prevention.
Fatemeh Kafi +5 more
doaj +1 more source
Oxalate as a potent promoter of kidney stone formation
Frontiers in Medicine, 2023 Kidney stones are among the most prevalent urological diseases, with a high incidence and recurrence rate. Treating kidney stones has been greatly improved by the development of various minimally invasive techniques.
Tao Chen +19 more
doaj +1 more source
, 2018 Primary hyperoxaluria type 1 (PH1) is a rare life-threatening genetic disease related to glyoxylate metabolism and characterized by accumulation of calcium oxalate crystals.
Moya-Garzón, María Dolores +8 more
core +1 more source
ALLN-177, oral enzyme therapy for hyperoxaluria [PDF]
, 2019 PURPOSE: To evaluate the potential of ALLN-177, an orally administered, oxalate-specific enzyme therapy to reduce urine oxalate (UOx) excretion in patients with secondary hyperoxaluria.
Lingeman, James E. +6 more
core +1 more source
Protective effects of ethanolic extract of Cuscuta reflexa Roxb. against ethylene glycol-induced hyperoxaluria and urolithiasis in rats [PDF]
Journal of HerbMed PharmacologyIntroduction: Renal urolithiasis is a prevalent global health concern due to its high recurrence rate. Cuscuta reflexa (Roxb) has been traditionally used for its anti-inflammatory and antioxidant properties.
Madan L. Kaushik +2 more
doaj +1 more source
Hyperoxaluria: a gut–kidney axis? [PDF]
, 2011 Hyperoxaluria leads to urinary calcium oxalate (CaOx) supersaturation, resulting in the formation and retention of CaOx crystals in renal tissue. CaOx crystals may contribute to the formation of diffuse renal calcifications (nephrocalcinosis) or stones ...
D'Haese, Patrick C. +11 more
core +1 more source
End Points for Clinical Trials in Primary Hyperoxaluria
, 2020 Patients with primary hyperoxaluria experience kidney stones from a young age and can develop progressive oxalate nephropathy. Progression to kidney failure often develops over a number of years, and is associated with systemic oxalosis, intensive ...
Milliner, Dawn S. +31 more
core +1 more source
Contributions of the anion exchangers SLC26A1, SLC26A2, SLC26A3, and SLC26A6 to intestinal oxalate transport in human Caco2‐BBE cells [PDF]
Physiol RepAbstract Kidney stones affect ~1 in 5 men and 1 in 11 women, with 70%–80% being composed of calcium oxalate. Knowing the contributions of anion exchangers SLC26A2 (A2), A3, and A6 to apical and A1 to basolateral oxalate transport in human intestinal Caco2‐BBE (C2) cells is important since enhancing intestinal oxalate secretion (A6/2/?A1) and reducing ...
Abdelhalim K +4 more
europepmc +2 more sources