Results 31 to 40 of about 9,955 (227)
Biomedicines, 2023 Chronic kidney disease (CKD) is a significant global public health concern associated with high morbidity and mortality rates. The maintenance of oxalate homeostasis plays a critical role in preserving kidney health, particularly in the context of CKD ...
Natalia Stepanova
doaj +1 more source
A test of the hypothesis that oxalate secretion produces proximal tubule crystallization in primary hyperoxaluria type I [PDF]
, 2013 The sequence of events by which primary hyperoxaluria type 1 (PH1) causes renal failure is unclear. We hypothesize that proximal tubule (PT) is vulnerable because oxalate secretion raises calcium oxalate (CaOx) supersaturation (SS) there, leading to ...
Coe, Fredric L. +7 more
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Clinical Case Reports, 2023 The current study is important in informing clinicians about the possibility of concurrent oxalate nephropathy caused by Roux‐en‐Y gastric bypass, high oxalate materials, and high‐dose vitamin C intake for COVID‐19 prevention.
Fatemeh Kafi +5 more
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Vitamin C-Induced Oxalate Nephropathy
International Journal of Nephrology, 2011 Although a multitude of syndromes have been thoroughly described as a result of vitamin deficiencies, over consumption of such substances may also be quite dangerous.
Jorge Lamarche +3 more
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Oxalate as a potent promoter of kidney stone formation
Frontiers in Medicine, 2023 Kidney stones are among the most prevalent urological diseases, with a high incidence and recurrence rate. Treating kidney stones has been greatly improved by the development of various minimally invasive techniques.
Tao Chen +19 more
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Formación de calculos renales de oxalato cálcico en mamíferos [PDF]
, 2010 Calcium oxalate (CaOx) is the main inorganic component of urolithiasis and is mainly present in the formation of kidney stones in humans. Additionally, oxalocalcic urolithiasis has become the most frequent type of kidney stones, for instance, oxalocalcic
Neira-Carrillo, Andrónico +1 more
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Protective effects of ethanolic extract of Cuscuta reflexa Roxb. against ethylene glycol-induced hyperoxaluria and urolithiasis in rats [PDF]
Journal of HerbMed PharmacologyIntroduction: Renal urolithiasis is a prevalent global health concern due to its high recurrence rate. Cuscuta reflexa (Roxb) has been traditionally used for its anti-inflammatory and antioxidant properties.
Madan L. Kaushik +2 more
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Genetic Correction of the Most Common Mutation Causing Primary Hyperoxaluria Restores Enzyme Localization and Oxalate Metabolism. [PDF]
J Inherit Metab DisABSTRACT Our research aimed to model primary hyperoxaluria type 1 in vitro using a stem cell model and assess the potential of adenine base editors in correcting the most common pathogenic AGXT genetic variant, c.508G>A (Gly170Arg), which leads to oxalate accumulation due to alanine‐glyoxylate aminotransferase mislocalization.
Keskinen T +9 more
europepmc +2 more sources
Late onset primary hyperoxaluria after kidney transplantation in a 36-year-old woman [PDF]
Journal of NephropathologyPrimary hyperoxaluria is a rare congenital autosomal recessive disorder disrupting the glyoxylate metabolism pathway in the liver. Type1 primary hyperoxaluria is caused by a deficiency in a specific liver enzyme namely, alanine glyoxylate ...
Amirhesam Alirezaei +4 more
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The role of lipid and lipoprotein metabolism in non-alcoholic fatty liver disease [PDF]
, 2017 Due to the epidemic of obesity across the world, nonalcoholic fatty liver disease (NAFLD) has become one of the most prevalent chronic liver disorders in children and adolescents.
Anania, Caterina +4 more
core +2 more sources