Results 121 to 130 of about 2,033,277 (389)

Improving Policy-Constrained Kidney Exchange via Pre-Screening [PDF]

arXiv, 2020
In barter exchanges, participants swap goods with one another without exchanging money; exchanges are often facilitated by a central clearinghouse, with the goal of maximizing the aggregate quality (or number) of swaps. Barter exchanges are subject to many forms of uncertainty--in participant preferences, the feasibility and quality of various swaps ...
arxiv  

Integrated Kidney Exosome Analysis for the Detection of Kidney Transplant Rejection.

ACS Nano, 2017
Kidney transplant patients require life-long surveillance to detect allograft rejection. Repeated biopsy, albeit the clinical gold standard, is an invasive procedure with the risk of complications and comparatively high cost. Conversely, serum creatinine
Jongmin Park, Hsing-Ying Lin, J. Assaker, Sangmoo Jeong, Chen-Han Huang, A. Kurdi, Kyungheon Lee, Kyle Fraser, Changwook Min, Siawosh K. Eskandari, Sujit Routray, B. Tannous, R. Abdi, L. Riella, A. Chandraker, Cesar M. Castro, R. Weissleder, Hakho Lee, J. Azzi   +18 more
semanticscholar   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

Efficacy of Adjunct Hemoperfusion Compared to Standard Medical Therapy on 28-Day Mortality in Leptospirosis Patients with Renal Failure and Shock: A Single-Center Randomized Controlled Trial

Tropical Medicine and Infectious Disease
Hemoperfusion is a novel adjunct therapy that targets the dysregulated inflammatory events in severe sepsis. Previous studies have reported conflicting results on its efficacy and safety.
Danice Romagne Leano, Romina Danguilan, Mel-Hatra Arakama, Vince Apelin, Paolo Pinkerton Alamillo, Eric Chua   +5 more
doaj   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Imlifidase in kidney transplantation

Clinical Kidney Journal
ABSTRACT Kidney transplantation, the gold-standard therapeutic approach for patients with end-stage kidney disease, offers improvement in patient survival and quality of life. However, broad sensitization against human leukocyte antigens often resulting in a positive crossmatch against the patient's living donor or the majority of ...
Mehmet Kanbay, Sidar Copur, Mustafa Guldan, Ahmet U Topcu, Lasin Ozbek, Baris Hasbal, Caner Süsal, Burak Kocak, Jasper Callemeyn, Mårten Segelmark   +9 more
openaire   +4 more sources

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van der Veen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
wiley   +1 more source

Acute kidney injury and tacrolimus toxicity in a kidney transplant recipient treated with nirmaltrevir/ritonavir: a case report

Journal of Medical Case Reports
Background Kidney transplant recipients with severe acute respiratory syndrome-coronavirus-2 infection have an increased risk of severe disease and mortality.
Jack Rycen, Julia Jefferis, David Mudge
doaj   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Advanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng, Ruizeng Luo, Ying Chen, Xiaoqiang Liu, Yuanyin Xi, Muhammad Usman, Xupin Jiang, Zhou Li, Jiaping Zhang   +8 more
wiley   +1 more source

Checkpoint Inhibitors in Kidney Transplant Recipients and the Potential Risk of Rejection

American Journal of Transplantation, 2016
Enhancing anti-tumor T cell immunity with checkpoint inhibitor antibodies such as anticytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and antiprogram death 1 (PD-1) has shown significant clinical benefits in tumor regression and prolonged ...
T. Alhamad, K. Venkatachalam, G. Linette, D. Brennan   +3 more
semanticscholar   +1 more source