Results 201 to 210 of about 828,864 (314)

Onco-nephrology in kidney transplant recipients: challenges and evolving strategies. [PDF]

Front Immunol
Alfieri C, Simeoni M, Di Naro M, Mattinzoli D, Ikehata M, Armelloni S, Molinari P, Maggi M, Mella A, Regalia A, Verdesca S, Favi E, Cosmai L, Messa P, Castellano G.   +14 more
europepmc   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

The impact of tacrolimus variability on first year renal function in kidney transplant recipients: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Taran F, Türkmen E.
europepmc   +1 more source

Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment

Advanced Science, EarlyView.
Trogocytosis efficiency varies significantly among different tumor cells and is inversely related to their cortical stiffness; this efficiency dictates the extent of immunosuppression via upregulation of CXCL5 and Arg‐1, ultimately driving CD8+T cell exhaustion and tumor escape.
Chao Liang, Jiaqi He, Wan‐Ru Zhuang, Yao Lei, Yanru Jiang, Xianbin Ma, Pan Liu, Zhujun Jiang, Yongheng Li, Hai‐Yan Xie   +9 more
wiley   +1 more source

WCN25-967 REGULAR USE OF TACROLIMUS GENOTYPE TEST AND USE OF FLUCONAZOLE IN FAST METABOLIZERS TO ACHIVE THERAPEUTIC DRUG LEVELS POST KIDNET TRANSPLANTATION

Kidney International Reports
smriti sinha, Sudheer Pandey, Shriram Kabra, Vivek Bansal   +3 more
doaj   +1 more source

Barriers to kidney transplant referral in the state of Minas Gerais: nephrologists' perspectives. [PDF]

J Bras Nefrol
Nogueira CM, Martins LC, Sanders-Pinheiro H.   +2 more
europepmc   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Factors Associated With Weight Management Referral Acceptance and Uptake in Kidney Transplant Candidates. [PDF]

Clin Transplant
Lavenburg LM, Morford H, Stark S, Kamat S, Mendoza MS, Molinari M, Puttarajappa C.   +6 more
europepmc   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Metabolic Syndrome and Cardiovascular Outcomes in Pediatric Kidney Transplant Recipients-A Cross-Sectional Study. [PDF]

Pediatr Transplant
Saha A, Champaneri B, Patel V, Shah H, Kapadia S, Vala K, Bhatt D, Patel H, Gera D, Modi M, Modi P.   +10 more
europepmc   +1 more source