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Immunosuppression and Kidney Transplantation
2021Immunosuppression is complex, fraught with on-target and off-target adverse effects, and hard to get right but is the key to successful allotransplantation. Herein, we review the key immunosuppressive agent classes used for kidney transplant, highlighting mechanisms of action and typical clinical use.
Jeanne, Kamal, Alden, Doyle
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Laparoscopic Kidney Transplantation
European Urology, 2010We present the details of the first laparoscopic transplantation of a kidney from a living, related donor, performed April 16, 2009. Surgical and functional results were acceptable. Surgical time was 240 min (53 min for vascular suture), with blood loss of 300 cm(3) and a hospital stay of 14 d. Serum creatinine at discharge was 73 mmol/l.
Rosales, A +9 more
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Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2009
International ...
Pillot, P., Kleinclauss, François, M.
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International ...
Pillot, P., Kleinclauss, François, M.
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Hypertension and kidney transplantation
Current Opinion in Nephrology and Hypertension, 1986Hypertension in kidney transplant patients is a common complication that affects long-term patient and allograft survival. Although multifactorial in nature, at least two causes can be corrected by surgical or radiologic intervention--stenosis and native kidney-associated hypertension.
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Transplantation: Kidney, Kidney–Pancreas Transplant
2014With in-depth understanding of transplant immunology, more sensitive assays have been developed for immunological risk assessment, crossmatch, and detection of donor-specific antibodies. The discovery of potent immunosuppressive drugs has successfully reduced the risk of acute rejection and graft loss from rejection.
Rubin Zhang, Anil Paramesh
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Matchability in kidney transplantation
Tissue Antigens, 1988The matchablity of a patient awaiting kidney transplantation is his propensity for being ‘well‐matched’. We present two methods for estimating matchability. It is commonly supposed that phenotype frequency is a good predictor of matchability. We show a correlation of only 0.3 between matchability and phenotype frequency using the definition of ‘well ...
W R, Gilks, S M, Gore, B A, Bradley
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IMMUNIZATION IN KIDNEY TRANSPLANTATION
2022Immunization towards Human Leukocyte Antigens (HLA) can occur through pregnancy, blood transfusion, or previous transplant. Determination of unacceptable and acceptable HLA antigen mismatches is a critical decision step in finding a suitable donor for the HLA immunized kidney recipients.
Burek Kamenarić, Marija +6 more
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Hyperuricemia in Kidney Transplantation
2004Hyperuricemia is a common problem among renal transplant recipients. Its prevalence is clearly attributable to cyclosporine (CsA) use, although individual patients may have other risk factors as well. CsA lowers the urinary clearance of uric acid. The specific mechanism for this is unknown, but may involve alteration in tubular transport. Hyperuricemia
Norberto, Perico +3 more
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Complement in Kidney Transplantation
Transplantation ReviewsTransplantation is the treatment of choice in most patients with kidney failure. The complement system plays a vital role in transplantation. The complement system forms a major part of innate immunity and acts as a bridge between innate and acquired immunity.
Pooja, Lokkur, Shyam Bihari, Bansal
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