Results 231 to 240 of about 333,176 (311)

Increased Treg in Kidney Transplant Recipients With Erythrocytosis. [PDF]

open access: yesTranspl Int
Bigatti C   +8 more
europepmc   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin   +2 more
wiley   +1 more source

Efficacy and Safety of Finerenone in Kidney Transplant Patients. [PDF]

open access: yesJ Clin Med
Kahvecioglu S   +5 more
europepmc   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang   +4 more
wiley   +1 more source

Diagnostical Performances of the FilmArray Gastro-Intestinal Panel in Kidney Transplant Recipients. [PDF]

open access: yesTranspl Int
Ferrie E   +9 more
europepmc   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen   +10 more
wiley   +1 more source

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