Results 61 to 70 of about 2,298,895 (410)

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Reverse Transplant Tourism [PDF]

, 2014
In this article, we propose a novel form of kidney swap, which we label “Reverse Transplant Tourism.” This proposal has the potential to increase the number of successful transplants in the US at a time of great need, while reducing costs.
Krawiec, Kimberly D., Rees, Michael A.
core   +2 more sources

A Pre-transplant Blood-based Lipid Signature for Prediction of Antibody-mediated Rejection in Kidney Transplant Patients [PDF]

, 2020
Purpose. The aim of this study is to demonstrate the potential of the pre-transplant lipidome to predict post-transplant antibody-mediated rejection (AMR) in kidney transplant patients. Methods.
Al sultan, Monther, Alshammari, Suad, Bobba, Sindhura, Contaifer, Daniel, Jr., Gupta, Gaurav, Kimball, Pamela, King, Anne, Kumar, Dhiren, Levy, Marlon, Morriss, Joshua, Stern, Jeffrey, Wijesinghe, Dayanjan   +11 more
core   +1 more source

Who should be prioritized for renal transplantation?: Analysis of key stakeholder preferences using discrete choice experiments [PDF]

, 2012
Background Policies for allocating deceased donor kidneys have recently shifted from allocation based on Human Leucocyte Antigen (HLA) tissue matching in the UK and USA. Newer allocation algorithms incorporate waiting time as a primary factor, and in
A Allepuz, AJ Lloyd, Ala Szczepura, Anil Gumber, C Byrne, C Byrne, CC Geddes, CJ Browning, Dennis Leech, Department of Health, DJ Street, Domenico Moro, FP Cappuccio, G Rubin, J Huber, J Neuberger, J Ratcliffe, J Ratcliffe, JM Wooldridge, K Ladkin, KC Norris, LF Ross, M Amaya-Amaya, M Bradley, MD Clark, Michael D Clark, NHS Blood and Transplant, NHS Blood and Transplant [formally UK Transplant], Nick West, ON Louis, PL Tso, R Bennett, RA Koenne, RM Higgins, Robert Higgins, S Youngkong, SN Davison, VB Ashby, VS Raleigh   +38 more
core   +4 more sources

Early clinical experience using donor‐derived cell‐free DNA to detect rejection in kidney transplant recipients

American Journal of Transplantation, 2019
Donor‐derived cell‐free DNA (dd‐cfDNA) became Medicare reimbursable in the United States in October 2017 for the detection of rejection in kidney transplant recipients based on results from its pivotal validation trial, but it has not yet been externally
E. Huang, S. Sethi, A. Peng, Reiad Najjar, J. Mirocha, M. Haas, A. Vo, S. Jordan   +7 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Differences in Proinflammatory Cytokines and Monocyte Subtypes in Older as Compared With Younger Kidney Transplant Recipients. [PDF]

, 2018
Background:The number of elderly patients with end-stage kidney disease requiring kidney transplantation continues to grow. Evaluation of healthy older adults has revealed proinflammatory changes in the immune system, which are posited to contribute to ...
Abdalla, Basmah, Bunnapradist, Suphamai, Danovitch, Gabriel, Groysberg, Victoria, Korin, Yael, Liang, Emily C, Lum, Erik, Pham, Phuong-Thu, Reed, Elaine F, Rossetti, Maura, Schaenman, Joanna, Sidwell, Tiffany, Sunga, Gema, Vangala, Sitaram   +13 more
core   +1 more source

Laparoscopic Kidney Transplantation

European Urology, 2010
We present the details of the first laparoscopic transplantation of a kidney from a living, related donor, performed April 16, 2009. Surgical and functional results were acceptable. Surgical time was 240 min (53 min for vascular suture), with blood loss of 300 cm(3) and a hospital stay of 14 d. Serum creatinine at discharge was 73 mmol/l.
Rosales, A, Salvador, JT, Urdaneta, G, Patino, D, Montlleo, M, Esquena, S, Caffaratti, J, de Leon, JP, Guirado, L, Villavicencio, H   +9 more
openaire   +3 more sources

Management of Kidney Transplant Recipients by General Nephrologists: Core Curriculum 2019.

American Journal of Kidney Diseases, 2019
Kidney transplantation is associated with improvement in quality of life and mortality as compared to remaining on dialysis. It is therefore the optimal treatment for kidney failure for most patients.
Santhi Voora, D. Adey
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source