Results 91 to 100 of about 2,281,812 (411)

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan, Hyunjin Kim, Bomin Kim, Honglin Piao, Joon Young Jang, Tae Kyeom Kang, Wook‐Bin Lee, Dohyeon Kim, Seunghyun Jo, Duckhyang Shin, Sharif MD Abuzar, Myung L. Kim, Jaeseok Yang, Sangyong Jon   +13 more
wiley   +1 more source

Hemophagocytic lymphohistiocytosis secondary to virus infection and followed by lupus nephritis recurrence in a renal transplantation pediatric recipient: a case report

BMC Nephrology, 2023
Background Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening disorder characterized by systemic inflammation and organ failure as a result of dysregulated immune cell activation.
Jiyuan Li, Chen Gao, Xuejing Zhu, Danyi Yang, Wendan Mao, Hengchang Yao, Mingyang Deng, Liang Tan, Helong Dai, Xubiao Xie, Longkai Peng, Fenghua Peng   +11 more
doaj   +1 more source

Organ Entrepreneurs [PDF]

, 2017
The supply of human organs for transplantation might seem an unlikely place to begin thinking about entrepreneurship. After all, there is no production market for human organs and, with the surprising exception of Iran, legal rules around the world make ...
Healy, Kieran, Krawiec, Kimberly D.
core   +2 more sources

Changes in Deceased Donor Kidney Transplantation One Year After KAS Implementation

American Journal of Transplantation, 2016
After over a decade of discussion, analysis, and consensus‐building, a new kidney allocation system (KAS) was implemented on December 4, 2014. Key goals included improving longevity matching between donor kidneys and recipients and broadening access for ...
D. Stewart, A. Kucheryavaya, D. Klassen, N. Turgeon, R. Formica, M. Aeder   +5 more
semanticscholar   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study

BMC Urology, 2020
Background For patients over the age of 70 years, sacral neuromodulation (SNM) is often not considered a potential therapeutic option. We therefore report on our results from performing SNM in elderly patients ≥70 years.
Sandra Schönburg, Tobias Bukethal, Paolo Fornara   +2 more
doaj   +1 more source

Pancreas Transplantation [PDF]

, 2009
The first successful pancreas transplantation in conjunction with a simultaneous kidney transplantation was performed in 1966 by Kelly, Lillehei and others from the University of Minnesota.
Shyr, Yi-Ming
core   +2 more sources

A comparative analysis of survival of patients on dialysis and after kidney transplantation

Clinical Kidney Journal, 2017
Background Kidney transplant survival benefits are not observed for around 8 months after transplantation because of a higher complications rate in early post-transplant periods.
M. Kaballo, M. Canney, P. O’Kelly, Y. Williams, C. O’Seaghdha, P. Conlon   +5 more
semanticscholar   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Kidney Transplantation in Children

New England Journal of Medicine, 2014
This review discusses unique aspects of kidney transplantation in children that necessitate specialized approaches and have resulted in clinical advances so that kidney transplantations in young children have higher success rates than in any other age group.
V. R. Dharnidharka, P. Fiorina, W. E. Harmon   +2 more
openaire   +4 more sources