Results 121 to 130 of about 2,367,532 (360)

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang   +11 more
wiley   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom

open access: yes, 2010
Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation.
Sam Machin   +8 more
core   +1 more source

Renal Autotransplantation for Complete Ureteral Avulsion Following Dilation and Curettage: A Rare Iatrogenic Complication

open access: yesResearch and Reports in Urology
Nabil Abdullah Al-Mughalis,1 Abudar Al-Ganadi,2 Ismail Al-Shameri,2 Naseem Al-Wsabi,2 Salem Bashraheel,3 Wail Abdo Ghaleb,1 Mohammed Ali Saeed,1 Nada Alwsabi2 1Department of Urology and Kidney Transplantation Surgery, Cardiovascular and Kidney ...
Al-Mughalis NA   +7 more
doaj  

COVID-19 and hospital activity: experience of the Nephrology Department of Ibn Sina Hospital-Rabat

open access: yesThe Egyptian Journal of Internal Medicine
The COVID-19 pandemic has led to a major health crisis, responsible for a very high morbidity in the world. This context represented an organizational challenge and required an adaptation of health services.
Sara El Maakoul   +3 more
doaj   +1 more source

ABO-Incompatible Kidney Transplantation

open access: yesFrontiers in Immunology, 2017
ABO-incompatible (ABOi) kidney transplantation has long been considered a contraindication to successful kidney transplantation. During the last 25 years, increasing organ shortage enforced the development of strategies to overcome the ABO antibody ...
C. Morath   +4 more
semanticscholar   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]

open access: yes, 2004
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Lederer, Stephan R.   +5 more
core   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

Life on the list: an exploratory study of the life world of individuals waiting for a kidney transplant

open access: yes, 2010
Kidney transplantation is the treatment of choice for many individuals with end stage renal disease (ESRD), as transplantation is reported to offer a greater quality of life than renal dialysis.
Long-Sutehall, Tracy   +4 more
core  

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