Results 141 to 150 of about 2,367,532 (360)

Reference values and physiological characterization of a specific isolated pig kidney perfusion model

, 2007
Background: Models of isolated and perfused kidneys are used to study the effects of drugs, hazardous or toxic substances on renal functions. Since physiological and morphological parameters of small laboratory animal kidneys are difficult to compare to ...
Unger Volker, David A Groneberg, Fischer, Axel, Unger, Volker, Groneberg, Jan David Alexander, Groneberg David A, Volker Unger, Grosse-Siestrup Christian, Fehrenberg Claudia, Meissler, Michael, Axel Fischer, Christian Grosse-Siestrup, Fischer Axel, Meissler Michael, Michael Meissler, Grosse-Siestrup, Christian, Fehrenberg, Claudia, Claudia Fehrenberg   +17 more
core   +1 more source

Biopsy-Proven T-Cell Mediated Rejection After Belatacept Rescue Conversion: A Multicenter Retrospective Study

Transplant International
After kidney transplantation, conversion to belatacept is a promising alternative in patients with poor graft function or intolerance to calcineurin inhibitors. The risk of acute rejection has not been well described under these conditions.
Dominique Bertrand, Nathalie Chavarot, Jérôme Olagne, Clarisse Greze, Philippe Gatault, Clément Danthu, Charlotte Colosio, Maïté Jaureguy, Agnès Duveau, Nicolas Bouvier, Yannick Le Meur, Léonard Golbin, Eric Thervet, Antoine Thierry, Arnaud François, Charlotte Laurent, Mathilde Lemoine, Dany Anglicheau, Dominique Guerrot   +18 more
doaj   +1 more source

Endothelial Dysfunction in Kidney Transplantation

Frontiers in Immunology, 2018
Kidney transplantation entails a high likelihood of endothelial injury. The endothelium is a target of choice for injury by ischemia-reperfusion, alloantibodies, and autoantibodies. A certain degree of ischemia-reperfusion injury inevitably occurs in the
H. Cardinal, M. Dieudé, M. Hébert
semanticscholar   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source

Etelcalcetide use During Maintenance Hemodialysis and Incidence of Parathyroidectomy After Kidney Transplantation.

Etelcalcetide is an i.v. calcimimetic agent, effectively reducing parathyroid hormone levels in patients on maintenance hemodialysis (HD). The clinical impact of discontinuing etelcalcetide at the time of kidney transplantation is unknown.
Jadoul, Michel, Labriola, Laura, Iriarte, Miren, Delaey, Philippe, Mourad, Michel, Kanaan, Nada, Darius, Tom, Devresse, Arnaud, CUSL Kidney Transplantation Network Collaborators, Buemi, Antoine, Morelle, Johann, Faitatzidou, Danai, Goffin, Eric   +12 more
core   +1 more source

Competition and Post-Transplant Outcomes in Cadaveric Liver Transplantation under the MELD Scoring System [PDF]

Previous researchers have modelled the decision to accept a donor organ for transplantation as a Markov decision problem, the solution to which is often a control-limit optimal policy: accept any organ whose match quality exceeds some health-dependent ...
Alberto M. Segre, Jeffrey B. Halldorson, John P. Roberts, Harry J. Paarsch   +3 more
core   +2 more sources

The stuck haemodialysis catheter—a case report of a rare but dreaded complication following kidney transplantation

BMC Nephrology
Background Tunnelled cuffed haemodialysis catheters are at increased risk of incarceration or becoming ‘stuck’ via fibrotic adhesion to the central veins when left in situ for prolonged periods of time.
Cameron Burnett, S. Chandler, D. Jegatheesan, B. Pearch, A. Viecelli, D. W. Mudge   +5 more
doaj   +1 more source

Sensitization and Deceased-Donor Kidney Transplant Access in France

Kidney International Reports
Introduction: Highly sensitized kidney transplant candidates have reduced access to deceased-donor kidney transplantation (DDKT) and worse waitlist outcomes.
Dominique Bertrand, Philippe Gatault, Coralie Poulain, Charlotte Colosio, Clément Danthu, Agnès Duveau, Laure Ecotière, Cyril Garrouste, Yannick Le Meur, Marie-Pascale Morin, Valérie Châtelet, Sophie Caillard, Dany Anglicheau   +12 more
doaj   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source