Results 161 to 170 of about 398,508 (313)

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Kidney Transplantation in Advanced Octogenarians: The World's Oldest Kidney Transplant Recipient. [PDF]

Can J Kidney Health Dis
Angjeli A, Aboghanem A, Nash MM, Prasad GVR.   +3 more
europepmc   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Changes in maintenance immunosuppression after pediatric kidney transplantation-a report from the Nordic pediatric kidney transplantation registry. [PDF]

Pediatr Nephrol
Kaijansinkko H, Tainio J, Bjerre A, Gjerstad AC, Weinreich IDS, Jalanko H, Wennberg L, Westphal Ladfors S, Thiesson HC, Bekassy Z, Sørensen SS, Jahnukainen T.   +11 more
europepmc   +1 more source

Incidence of fistulas following human pancreas transplantation [PDF]

, 1987
Abendroth, D., Gottwald, T., Illner, Wolf-Dieter, Land, Walter   +3 more
core   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source

WCN24-741 LONG-TERM OUTCOMES OF RENAL TRANSPLANTATION IN CHILDREN WEIGHING LESS THAN 10 KG

Kidney International Reports
PAULO Koch Nogueira, Maria Fernanda Camargo, Luciana Feltran, José Carlos Baptista   +3 more
doaj   +1 more source

Immune Landscape in Kidney Transplantation. [PDF]

J Inflamm Res
Niu D, Chen R, Pang X.
europepmc   +1 more source

Body Mass Index: A Key Factor in Surgical Site Infections After Kidney Transplantation? [PDF]

Int Wound J
El-Mahrouk M, Sorgnitt R, Schwantzer G, Karitinig R, Jaradat D, Mathe Z, Sucher R, Kniepeiss D.   +7 more
europepmc   +1 more source

A Case of Post-Transplantation Lymphoproliferative Disorder Following Kidney Transplantation. [PDF]

Case Rep Nephrol
Raval PA, Odhiambo JO, Patel H, Sokwala A.   +3 more
europepmc   +1 more source