Results 161 to 170 of about 2,170,450 (367)

EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non‐Small Cell Lung Cancer via Hippo Pathway Activation

Advanced Science, EarlyView.
EM2 directly binds to and activates MST1/2, enhancing their kinase activity and sequentially promoting LATS phosphorylation, which increases YAP phosphorylation. Consequently, YAP nuclear translocation is suppressed, leading to reduced transcription of downstream targets CTGF and CYR61, ultimately exerting a robust inhibitory effect on NSCLC cell ...
Siyu Yang, Huayan Xie, Qiang Lin, Liujin Zhou, Junxi Liu, Zekai Fang, Ziling Tang, Ruijie Yuan, Jinxuan Su, Sijia Li, Wenlin Wang, Mingyu Pan, Hao Wang, Xiaoyong Dai, Guocai Wang, Yubo Zhang   +15 more
wiley   +1 more source

Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial [PDF]

, 2022
Seychelle Yohanna, Mackenzie Wilson, Kyla L. Naylor, Amit X. Garg, Jessica M. Sontrop, Dmitri Belenko, Lori Elliott, Susan McKenzie, Sara Macanovic, István Mucsi, Rachel E. Patzer, Irina Voronin, Iris Lui, Peter G. Blake, Amy D. Waterman, Darin Treleaven, Justin Presseau   +16 more
openalex   +1 more source

Functions of a Transplanted Kidney [PDF]

Science, 1905
A, Carrel, C C, Guthrie
openaire   +2 more sources

Delayed Graft Function: The AKI of Kidney Transplantation

Nephron, 2018
R. Mannon
semanticscholar   +1 more source

FXYD3 Promotes Tumor Progression by Binding With IRF7 to Regulate JAK2/STAT5 Signaling in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
FXYD3 binds IRF7 via its 60–87aa domain, triggering a cGAS/STING‐mediated positive feedback loop amplified by type I interferon. This sustains JAK2/STAT5 activation, accelerating ICC progression. Targeting FXYD3 with siFXYD3@PEP suppresses tumors and enhances chemotherapy sensitivity. Abstract Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis,
Yan Zhou, Xiaofeng Shen, Shuo Zhang, XiaoHong Pu, Zipeng Xu, Xiang Zhao, Wei Feng, Yuan Liang, Xingtao He, Aihua Yang, Yudong Qiu, Yihang Yuan, Chaobo Chen, Jun Chen   +13 more
wiley   +1 more source

Proteinuria After Kidney Transplantation. [PDF]

Pediatr Transplant
Seeman T, Myette RL, Feber J, Bertacchi M, Dandamudi RS, Erez DL, Buescher A.   +6 more
europepmc   +1 more source

Belatacept and Long-Term Outcomes in Kidney Transplantation.

New England Journal of Medicine, 2016
F. Vincenti, L. Rostaing, J. Grinyo, K. Rice, S. Steinberg, L. Gaite, M. Moal, G. Mondragón-Ramírez, J. Kothari, M. Polinsky, H. Meier‐Kriesche, S. Munier, C. Larsen   +12 more
semanticscholar   +1 more source

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source

Immune Landscape in Kidney Transplantation. [PDF]

J Inflamm Res
Niu D, Chen R, Pang X.
europepmc   +1 more source

Optimizing Detection of Kidney Transplant Injury by Assessment of Donor-Derived Cell-Free DNA via Massively Multiplex PCR [PDF]

, 2018
Tara K. Sigdel, Felipe Acosta Archila, T Constantin, Sarah A. Prins, Juliane Liberto, Izabella Damm, Parhom Towfighi, Samantha Navarro, Eser Kırkızlar, Zachary Demko, Allison Ryan, Styrmir Sigurjonsson, Reuben D. Sarwal, Szu-Chuan Hseish, Chitranon Chan‐on, Bernhard Zimmermann, Paul R. Billings, Solomon Moshkevich, Minnie Sarwal   +18 more
openalex   +1 more source