Results 41 to 50 of about 2,292,383 (315)

miR-136 improves renal fibrosis in diabetic rats by targeting down-regulation of tyrosine kinase SYK and inhibition of TGF-β1/Smad3 signaling pathway

Renal Failure, 2020
Objective To investigate the way that miR-136 regulated spleen tyrosine kinase (SYK) and transforming growth factor-β1 (TGF-β1)/Smad3 signaling pathways on renal fibrosis.
Lei Liu, Xinlu Pang, Wenjun Shang, Guiwen Feng, Zhigang Wang, Junxiang Wang   +5 more
doaj   +1 more source

Is Bigger Better? Living Donor Kidney Volume as Measured by the Donor CT Angiogram in Predicting Donor and Recipient eGFR after Living Donor Kidney Transplantation

Journal of Transplantation, 2021
Background. The role of kidney volume measurement in predicting the donor and recipient kidney function is not clear. Methods. We measured kidney volume bilaterally in living kidney donors using CT angiography and assessed the association with the donor ...
Chaudhry Adeel Ebad, David Brennan, Julio Chevarria, Mohammad Bin Hussein, Donal Sexton, Douglas Mulholland, Ciaran Doyle, Patrick O’Kelly, Yvonne Williams, Ruth Dunne, Conall O’Seaghdha, Dilly Little, Martina Morrin, Peter J. Conlon   +13 more
doaj   +1 more source

Combined liver-kidney transplantation and the effect of preformed lymphocytotoxic antibodies [PDF]

, 1994
Thirty-eight sequentially placed liver and kidney allografts were evaluated with respect to patient and graft survival, and the influence of preformed lymphocytotoxic antibodies was analysed.
A.Jake Demetris, Calne, Demetris, Duquesnoy, Eid, Ellis, Flye, Fung, Fung, Furuya, George Mazariegos, Gonwa, Gordon, Gordon, Gugenheim, Hector Ramos, Iwaki, Jerry McCauley, John J. Fung, Kamada, Kissmeyer-Nielsen, Margreiter, Margreiter, McCauley, Moore, Rene J. Duquesnoy, Ron Shapiro, Starzl, Susan L. Saidman, Takaya, Takaya, Takaya, Thomas E. Starzl, Vogel, Weber   +34 more
core   +1 more source

Correlation of serum soluble Klotho with fibroblast growth factor 23 levels in chronic kidney disease patients; a single centre study [PDF]

Journal of Nephropharmacology, 2020
Introduction: Klotho is a single-pass transmembrane protein with a long extracellular domain and short cytoplasmic tail that appears to modulate aging. Objectives: This cross-sectional investigation was conducted at a tertiary care centre to find the
Yuvaraj Anand, Vijayan Madhusudan, Parthasarathy Rajeevalochana, Mathew Milly, George Deepu, Abraham Georgi   +5 more
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation

Current drug metabolism, 2018
Background: Tacrolimus (Tac, or FK506), a calcineurin inhibitor (CNI), is the first-line immu-nosuppressant which consists of the footstone as immunosuppressive regimens in kidney transplantation.
Meng Yu, Mou-Ze Liu, Wei Zhang, Y. Ming
semanticscholar   +1 more source

Soil Chemical Properties Under Conservation Agriculture and Cereal-Based Cropping System in Eastern Tarai of Nepal [PDF]

, 2020
Field experiments were conducted for four years (2014-2017) at five locations namely Salbani, Bhokraha, Simariya, Bhaluwa and Kaptanganj of Sunsari district to assess the changes in soil chemical properties under conservation agriculture (CA)-based ...
Gyawaly, P. (Pankaj), Jha, S. K. (Sanjeet), Khadka, D. (Dinesh), Paneru, P. (Prakash), Shrestha, J. (Jiban), Shrestha, S. R. (Shukra)   +5 more
core  

A Prospective Study of Eplerenone in the Treatment of Patients with Glomerulonephritis

Biomedicines, 2023
Background: High aldosterone levels contribute to kidney disease progression, while spironolactone in combination with ACEi or ARBs can potentially reduce proteinuria and ameliorate kidney function deterioration.
Marios Papasotiriou, Georgia Andrianna Georgopoulou, Adamantia Mpratsiakou, Theodoros Ntrinias, Georgios Lyras, Dimitrios S. Goumenos, Evangelos Papachristou   +6 more
doaj   +1 more source

Alemtuzumab induction and tacrolimus monotherapy in pancreas transplantation: One- and two-year outcomes [PDF]

, 2006
BACKGROUND. Alemtuzumab (Campath-1H) induction with tacrolimus monotherapy has been shown to provide effective immunosuppression for kidney, liver, lung, and small bowel transplantation.
Abu-Elmagd, Akhtar Khan, Amadeo Marcos, Amit Basu, Calne, Ciano, Deanna Blisard, Flechner, Gruessner, Hale, Henkie P. Tan, John J. Fung, Kaufmann, Kirk, Knechtle, Knechtle, Kusum Tom, Marcos, Marcos, McCurry, Ngoc L. Thai, Ron Shapiro, Shapiro, Shapiro, Starzl, Starzl, Starzl, Starzl, Stuart, Thai, Thomas E. Starzl, Tryphonopoulos, Tzakis, Watson   +33 more
core   +1 more source

Over-expressed microRNA-181a reduces glomerular sclerosis and renal tubular epithelial injury in rats with chronic kidney disease via down-regulation of the TLR/NF-κB pathway by binding to CRY1

Molecular Medicine, 2018
Background MicroRNAs (miRNAs) contribute to the progression of chronic kidney disease (CKD) by regulating renal homeostasis. This study explored the effects of miR-181a on CKD through the Toll-like receptor (TLR)/nuclear factor-kappa B (NF-κB) pathway by
Lei Liu, Xin-Lu Pang, Wen-Jun Shang, Hong-Chang Xie, Jun-Xiang Wang, Gui-Wen Feng   +5 more
doaj   +1 more source

Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]

, 1973
The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L, HALGRIMSON, CHARLES G, KATZ, FRED H, LANOIS, BERNARD, PINNGGERA, WULF, POPOVTZER, MORDECAI M, ROBINETTE, JOHN, STARZL, THOMAS E   +7 more
core   +1 more source