Results 41 to 50 of about 273,215 (316)

The effect of foot orthoses on midfoot pain and the volume of bone marrow lesions in the midfoot: a randomized mechanism of action study

Arthritis Care &Research, Accepted Article.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain and MRI‐confirmed midfoot BMLs.
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, EarlyView.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source

Predictors and one-year outcomes of patients with delayed graft function after deceased donor kidney transplantation

BMC Nephrology, 2020
Background Delayed graft function (DGF) is closely associated with the use of marginal donated kidneys due to deficits during transplantation and in recipients. We aimed to predict the incidence of DGF and evaluate its effect on graft survival.
Rao Chen, Haifeng Wang, Lei Song, Jianfei Hou, Jiawei Peng, Helong Dai, Longkai Peng   +6 more
doaj   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

RECONSTRUCTIVE OPERATIONS ON THE PERMANENT VASCULAR ACCESS FOR HEMODIALYSIS

Вестник трансплантологии и искусственных органов, 2010
In patients with end stage renal failure it is vitally necessary to have permanent long functioning vascular access, providing all requirements of modern hemodialysis.
V. I. Lotts, L. E. Osipov, V. N. Sergeev
doaj   +1 more source

MicroRNAs in kidney transplantation [PDF]

Nephrology Dialysis Transplantation, 2014
The discovery of novel classes of non-coding RNAs (ncRNAs) has revolutionized medicine. Long thought to be a mere cellular housekeeper, surprising functions have recently been uncovered. MicroRNAs (miRNAs), are a representative of the class of short ncRNAs, play a fundamental role in the control of DNA and protein biosynthesis and activity as well as ...
J. Wilflingseder, R. Reindl-Schwaighofer, J. Sunzenauer, A. Kainz, A. Heinzel, B. Mayer, R. Oberbauer   +6 more
openaire   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Clinical outcomes of kidney transplantation from expanded-criteria donors and KDPI>85% kidneys in deceased Chinese donors

BMC Nephrology
Background Kidney transplantation is the optimal treatment for end-stage renal disease; however, the limited availability of donor kidneys hinders the advancement of this procedure.
Kankan Shui, Hedong Zhang, Tengfang Li, Jianfei Hou, Gongbin Lan, Fenghua Peng, Shaojie Yu, Xubiao Xie, Helong Dai, Longkai Peng   +9 more
doaj   +1 more source

Trends of kidney transplantation in Japan in 2018: data from the kidney transplant registry

Renal Replacement Therapy, 2019
The number of kidney transplants has gradually increased in the last decade; it was 1742 in Japan in 2017. The outcomes have improved year by year, with the indications for transplantation expanding accordingly.
Takashi Yagisawa, Makiko Mieno, Naotsugu Ichimaru, Ken Morita, Michio Nakamura, Kiyohiko Hotta, Takashi Kenmochi, Kenji Yuzawa   +7 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source