Results 41 to 50 of about 398,508 (313)

A Prospective Study of Eplerenone in the Treatment of Patients with Glomerulonephritis

Biomedicines, 2023
Background: High aldosterone levels contribute to kidney disease progression, while spironolactone in combination with ACEi or ARBs can potentially reduce proteinuria and ameliorate kidney function deterioration.
Marios Papasotiriou, Georgia Andrianna Georgopoulou, Adamantia Mpratsiakou, Theodoros Ntrinias, Georgios Lyras, Dimitrios S. Goumenos, Evangelos Papachristou   +6 more
doaj   +1 more source

Laparoscopic Kidney Transplantation

European Urology, 2010
We present the details of the first laparoscopic transplantation of a kidney from a living, related donor, performed April 16, 2009. Surgical and functional results were acceptable. Surgical time was 240 min (53 min for vascular suture), with blood loss of 300 cm(3) and a hospital stay of 14 d. Serum creatinine at discharge was 73 mmol/l.
Rosales, A, Salvador, JT, Urdaneta, G, Patino, D, Montlleo, M, Esquena, S, Caffaratti, J, de Leon, JP, Guirado, L, Villavicencio, H   +9 more
openaire   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Renal amyloidosis: a hidden complication of celiac disease (a case report)

The Egyptian Journal of Internal Medicine
We report a case of a 36-year-old female with untreated celiac disease, exhibiting both digestive discomfort and extra-digestive symptoms, including anemia. She subsequently developed a nephrotic syndrome. Biopsy of the accessory salivary gland confirmed
Zaineb Kaouiri, Ikram Ftaimi, Meryem Benbella, Rabia Bayahia, Loubna Benamar, Naima Ouzeddoun, Tarik Bouattar   +6 more
doaj   +1 more source

Mortality after kidney transplantation: 10-year outcomes

Cirugía y Cirujanos, 2022
Objectives: In the past decade, advances in immunological therapy have increased the survival of kidney recipients and their grafts. However, it has not achieved the desired level of improvement.
Turgut Piskin, Arife Simsek, Sait Murat-Dogan, Baha T. Demirbas, Bulent Unal, Ismail O. Yildirim, Sibel A. Toplu, Haci B. Berktas, Hatice Can, Ebru I. Coskun, Mukadder Sanli, Huseyin Gurbuz, Mehmet S. Arslan, Zeynep Piskin, Julide Yagmur, Fatih Oguz, Yasar Bayindir, Ozkan Ulutas, Hulya Taskapan, Idris Sahin   +19 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Longitudinal trajectories of the triglyceride-glucose index predict long-term major cardiovascular events in type 2 diabetes after simultaneous pancreas-kidney transplantation: a retrospective cohort study

Lipids in Health and Disease
Background With the rising proportion of recipients with type 2 diabetes (T2D) undergoing simultaneous pancreas-kidney transplantation (SPK), cardiovascular complications remain the leading cause of post-transplant mortality. However, tools for the early
Jianming Zheng, Yu Cao, Hui Wang, Xiaofeng Shi, Jianghao Wei, Liping Guo, Panpan Zhan, Wenli Song   +7 more
doaj   +1 more source

DISTAL SPLENORENAL VENOUS ANASTOMOSIS IN TREATMENT OF DIABETES MELLITUS

Вестник трансплантологии и искусственных органов, 2010
We studied the outcomes of the operations for distal splenorenal venous anastomosis of 134 patients with type 1 diabetes mellitus. We have noticed the significant improvement of patient’s general condition due to spasmolytic effect of glucagon, bypassed ...
T. I. Shraer, N. S. Rozina, A. A. Salmayer   +2 more
doaj   +1 more source

Assessment of hypertension-mediated organ damage in children and adolescents with hypertension

Blood Pressure, 2023
Purpose: Arterial hypertension (HT) is a main, potentially reversible cardiovascular risk factor. Long lasting HT leads to hypertension mediated organ damage (HMOD) of heart, vascular bed, and kidneys.
Michał Pac, Łukasz Obrycki, Jan Koziej, Krzysztof Skoczyński, Anna Starnawska-Bojsza, Mieczysław Litwin   +5 more
doaj   +1 more source