Results 101 to 110 of about 85,860 (310)

Continuous growth of proximal tubular kidney epithelial cells in hormone-supplemented serum-free medium. [PDF]

, 1982
An epithelial cell line from pig kidney (LLC-PK1) with properties of proximal tubular cells can be maintained indefinitely in hormone-supplemented serum-free medium. Continuous growth requires the presence of seven factors: transferrin, insulin, selenium,
Chuman, L, Cohen, AH, Fine, LG, Saier, MH   +3 more
core  

Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells [PDF]

, 2009
When the succinate receptor (SUCNR1) is activated in the afferent arterioles of the glomerulus it increases renin release and induces hypertension.
Deen, Fenton, Francke, Gimenez, Goldsmith, Graeme Milligan, He, Hems, Henrich, Hochachka, Horst Schweer, Janos Peti-Peterdi, Jassem, Joris H. Robben, Kang, Leslie, May, Murdoch, Nordmann, Pajor, Peter M.T. Deen, Raman, Robben, Robert A. Fenton, Rohrwasser, Rohrwasser, Sadagopan, Sakai, Sapieha, Sarah L. Vargas, Schweer, Tamma, Toma, van Beest, Vargas, Weinberg, Wittenberger, Zelenina   +37 more
core   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source

Signaling pathways involved in renal oxidative injury: role of the vasoactive peptides and the renal dopaminergic system [PDF]

, 2014
The physiological hydroelectrolytic balance and the redox steady state in the kidney are accomplished by an intricate interaction between signals from extrarenal and intrarenal sources and between antinatriuretic and natriuretic factors.
Choi, Marcelo Roberto, Della Penna, S. L., Fernandez, Belisario Enrique, Kouyoumdzian, Nicolás Martín, Kravetz, Maria Cecilia, Roson, Maria Ines, Rukavina Mikusic, Natalia Lucía   +6 more
core   +3 more sources

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

Arthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun, Yu Wang, Yongjing Cheng, Dongmei Guo, Jiankang Hu, Dongzhou Liu, Zhengnan Gao, Changgui Li, Yibing Lu, Xiaodan Kong, Yu Liu, Zhenyu Jiang, Bin Yi, Hongfeng Zhang, Baijie Xu, Shihao Yu, Rieko Kokan, Kohei Ishikawa, Mikiko Kawakatsu, Zhuoli Zhang   +19 more
wiley   +1 more source

MORPHOLOGICAL AND HISTOLOGICAL STUDY FOR THE KIDNEYS OF COOT BIRD ( Fulica atra ) [PDF]

Basrah Journal of Veterinary Research, 2012
Present study were carried out on ten adult males of coot bird, for determinate the histological structure of kidneys. The results were showed that each kidney consisted of three parts, a large cranial (mean of its length 28±0.15mm and its width13±0.08mm)
Abbas Lafi Batah
doaj   +1 more source

Boundary-Aware Network for Kidney Parsing [PDF]

arXiv, 2022
Kidney structures segmentation is a crucial yet challenging task in the computer-aided diagnosis of surgery-based renal cancer. Although numerous deep learning models have achieved remarkable success in many medical image segmentation tasks, accurate segmentation of kidney structures on computed tomography angiography (CTA) images remains challenging ...
arxiv  

Effect of hydration schedules on dose‐limiting toxicity in patients with head and neck squamous cell carcinoma treated with cisplatin

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to determine if head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin chemoradiotherapy and short hydration (SH) experience less dose‐limiting toxicity (DLT) and receive more cisplatin than those with medium hydration (MH) or long hydration (LH).
Anouk W. M. A. Schaeffers, Cassimy B. van Neerven, Dorieke van Balen, Mirjam Crul, Marije Slingerland, Saskia A. C. Luelmo, Jan Paul de Boer, Jens Voortman, Arjan D. van Zuilen, Remco de Bree, Lot A. Devriese   +10 more
wiley   +1 more source

The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506: Clinical significance and comparison with cyclosporine [PDF]

, 1993
The histopathological changes in 51 renal allograft biopsies from patients immunosuppressed with FK506 were compared with those seen in 30 needle biopsies obtained from patients on cyclosporine.
Demetris, AJ, Jordan, ML, Randhawa, PS, Shapiro, R, Starzl, TE   +4 more
core   +1 more source

Expression of metallothionein in renal tubules of rats exposed to acute and endurance exercise.

Folia Histochemica et Cytobiologica, 2006
The induction of exercise-induced apoptosis in not actively involved in exercise organs, such as kidney could be a result of oxidative stress. Metallothionein (MT) exerts a protective effect in the cell against oxidative stress and apoptosis.
Katia Rossini, Zbigniew Jethon, Marek Cegielski, Małgorzata Dumańska, Barbara Dolińska-Krajewska, Piotr Dziegiel, Marzena Podhorska-Okołów, Ugo Carraro, Maciej Zabel   +8 more
doaj   +1 more source