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Endopeptidases in the brush border of the kidney proximal tubule.
Ciba Foundation symposium, 1977Among the five peptidase known to be located in the microvillus membrane of the renal proximal tubule are two enzymes with endopeptidase activity. Neutral endopeptidase, a zinc-dependent enzyme, has a broad specificity comparable to that of thermolysin, and like the latter may be specifically inhibited by phosphoramidon.
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Effects of various cephalosporins on the proximal tubule of the human kidney
European Journal of Clinical Pharmacology, 1978Cephamandol 6.0 g, cephazolin 6.0 g or cephacetrile or cephalothin 8.0 g were administered as short-term infusions on 3 consecutive days to informed volunteers, who had no history or evidence of impairment of renal function. There were 15 subjects in the cephamandol, cephacetrile and cephalothin groups and 14 subjects in the cephazolin group.
A. W. Mondorf +7 more
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Oxidative Stress in the Kidney: Proximal Tubule Disorders
2010Redox changes initiate various cellular signals in the cells, and the redox environment can determine if a cell will proliferate, differentiate, or die. Imbalance of the redox status such as during oxidative stress can trigger a series of events, leading to cellular dysfunction.
Sara Terryn, Olivier Devuyst
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Energy Compartmentation and Active Transport in Proximal Kidney Tubules
1986The primary work of the kidney is active transport.1 It is a long-standing observation that a linear relationship exists between the rate of sodium reabsorption by the whole kidney and its rate of oxygen consumption.2,3 Since the oxygen is consumed at the mitochondria and the energy for active transport is used by the Na,K-ATPase located at the plasma ...
Stephen P. Soltoff +2 more
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Effects of cefotaxime on the proximal tubules of the human kidney
Journal of Antimicrobial Chemotherapy, 1980P. Burk +4 more
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Protein degradation in kidney proximal tubule cell monolayers
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1994Isolated proximal tubule cells have been labelled with L-[4,5-3H]leucine prior to cell division. Histochemical staining demonstrated the purity of the cultures. The bicarbonate ion or a collagen support was required for cell growth. Different culture growth rates were established by varying these parameters.
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Organization of the Kidney Proximal-Tubule Plasma Membrane
Biochemical Society Transactions, 1976A J Kenny, Andrew G. Booth
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Onconephrology: The intersections between the kidney and cancer
Ca-A Cancer Journal for Clinicians, 2021Mitchell H Rosner +2 more
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American Cancer Society's report on the status of cancer disparities in the United States, 2021
Ca-A Cancer Journal for Clinicians, 2022Farhad Islami +2 more
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Covid‐19 and kidney injury: Pathophysiology and molecular mechanisms
Reviews in Medical Virology, 2021Elham Ahmadian +2 more
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