Results 101 to 110 of about 620,224 (255)

Adult human CD133/1+ kidney cells isolated from papilla integrate into developing kidney tubules [PDF]

, 2011
Approximately 60,000 patients in the United States are waiting for a kidney transplant due to genetic, immunologic and environmentally caused kidney failure.
Angela Welford, Vincent H. Gattone, Gavin Pickett, Robert Bacallao, Bacallao, Robert, Scott A. Ness, Roitbak, Tamara, Elsa Romero, Ness, Scott A., Angela Wandinger-Ness, Tamara Roitbak, Wandinger-Ness, Angela, Romero, Elsa, Welford, Angela, Pickett, Gavin, Heather H. Ward, Gattone, Vincent H., Ward, Heather H.   +17 more
core   +1 more source

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

Animal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani, Mahnaz Torfeh, Fatemeh Ashrafian, Niloofar Rezaie, Mohsen Mohammadi, Shadi Aghamohammad, Mahdi Rohani   +6 more
wiley   +1 more source

A Subpopulation of Label-Retaining Cells of the Kidney Papilla Regenerates Injured Kidney Medullary Tubules [PDF]

, 2016
SummaryTo determine whether adult kidney papillary label-retaining cells (pLRCs) are specialized precursors, we analyzed their transcription profile. Among genes overexpressed in pLRCs, we selected candidate genes to perform qPCR and immunodetection of ...
Rosemary V. Sampogna, Qais Al-Awqati, Juan A. Oliver, Al-Awqati, Qais, Dahan, Alexander, Alexander Dahan, Zhang, Qing-Yin, Tian Huai Shen, Qing-Yin Zhang, Jalal, Sumreen, Shen, Tian Huai, Oliver, Juan A., Wang, Weiwei, Sumreen Jalal, Sampogna, Rosemary V., Weiwei Wang   +15 more
core   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

Protein handling in kidney tubules

The kidney proximal tubule reabsorbs and degrades filtered plasma proteins to reclaim valuable nutrients and maintain body homeostasis. Defects in this process result in proteinuria, one of the most frequently used biomarkers of kidney disease.
Hall, Andrew M; https://orcid.org/
core   +1 more source

Emerging key roles for P2X receptors in the kidney [PDF]

, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides.
Peppiatt-Wildman, Claire M., Peppiatt-Wildman, C. M., Wildman, S. S., R. E. Birch, C. M. Peppiatt-Wildman, Scott S Wildman, Schwiebert, E. M., Wildman, Scott S.P., E. M. Schwiebert, S. S. Wildman, Birch, R. E.   +10 more
core   +1 more source

Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions. [PDF]

Int J Mol Sci, 2023
Faria J, Ahmed S, Stamatialis D, Verhaar MC, Masereeuw R, Gerritsen KGF, Mihăilă SM.   +6 more
europepmc   +1 more source

Spatio-temporal expression of membrane transporters, Megalin and Cubilin, in renal development of C57BL/6 mice

陆军军医大学学报
Objective To observe the distribution of membrane transporters, Megalin and Cubilin, in the renal development of mice, and to reveal the temporal and spatial rules of their functional differentiation during renal development.
LUO Mei, ZHAI Xiaoyue, MA Yunsheng
doaj   +1 more source

ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules. [PDF]

J Clin Invest, 2023
Mukhi D, Li L, Liu H, Doke T, Kolligundla LP, Ha E, Kloetzer K, Abedini A, Mukherjee S, Wu J, Dhillon P, Hu H, Guan D, Funai K, Uehara K, Titchenell PM, Baur JA, Wellen KE, Susztak K.   +18 more
europepmc   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

The Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga, Verônica Oliveira‐Bahia, Maria Auxiliadora Ferreira, José Ribamar Felipe Marques, Diva Araújo Guimarães   +4 more
wiley   +1 more source