Results 141 to 150 of about 85,466 (268)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Lifestyle behaviours in children born extremely preterm at 2 years: a comparison to a Dutch reference population. [PDF]

open access: yesEur J Pediatr
Frerichs NM   +18 more
europepmc   +1 more source

Management of children in the deployed intensive care unit at Camp Bastion, Afghanistan. [PDF]

open access: yesJ R Army Med Corps, 2014
Inwald DP   +5 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Identification of a recessive <i>PCDH15</i> nonsense variant in purebred goats with vestibular dysfunction. [PDF]

open access: yesVet Anim Sci
Petzl E   +13 more
europepmc   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Bacillus spore probiotics for alleviating functional constipation in children: a randomized, double-blind, placebo-controlled trial. [PDF]

open access: yesCommun Med (Lond)
Nguyen HTL   +9 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Vertical transmission of Orf virus in goats and its prevention. [PDF]

open access: yesVet Res
Pang M   +9 more
europepmc   +1 more source

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