Results 81 to 90 of about 259,041 (316)

Natural killer cell-derived exosome-based cancer therapy: from biological roles to clinical significance and implications

Molecular Cancer
Natural killer (NK) cells are important immune cells in the organism and are the third major type of lymphocytes besides T cells and B cells, which play an important function in cancer therapy.
Chaohua Si, Jianen Gao, Xu Ma
doaj   +1 more source

Células natural killer e vigilância imunológica Natural killer cells and immune surveillance

Jornal de Pediatria, 2008
OBJETIVOS: Analisar a importância das células natural killer, de seus receptores killer immunoglobulin-like receptors e correspondentes genes (KIR) na vigilância imunológica do organismo contra agentes infecciosos, transplantes de células-tronco ...
Mariana Jobim, Luiz F. J. Jobim
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Tumor-Infiltrating Natural Killer Cells

, 2021
International audienceBecause of their potent antitumor activity and their proinflammatory role, natural killer (NK) cells are at the forefront of efforts to develop immuno-oncologic treatments.
Chiossone, Laura, Vivier, Eric, Narni-Mancinelli, Emilie, Cózar, Beatriz, Greppi, Marco, Carpentier, Sabrina, Vivier, Eric(Cozar and Greppi are CO-FIRST AUTHORS)   +6 more
core   +1 more source

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

Haematologica, 2016
We analyzed the impact of human cytomegalovirus infection on the development of natural killer cells in 27 pediatric patients affected by hematological malignancies, who had received a HLA-haploidentical hematopoietic stem cell transplantation, depleted ...
Letizia Muccio, Alice Bertaina, Michela Falco, Daniela Pende, Raffaella Meazza, Miguel Lopez-Botet, Lorenzo Moretta, Franco Locatelli, Alessandro Moretta, Mariella Della Chiesa   +9 more
doaj   +1 more source

Natural killer cytolytic activity

, 2010
Natural killer (NK)–mediated cellular killing has been extensively studied over the past 35 years and the current “granule exocytosis” model integrates work from many investigators to outline the primary means of NK cytotoxicity.
de Armas, Lesley R, Lesley R. de Armas, Podack, Eckhard R, Eckhard R. Podack   +3 more
core   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

Advanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam, Seon Yeong Chae, Young Woo Kwon, Hye Jin Heo, Hye Rin Lee, Ji Hyeok Lee, Dong‐Wook Han, Yun Hak Kim, Suck Won Hong   +8 more
wiley   +1 more source

Natural Killer Cell and Large Granular Lymphocyte Deficiency in the Gut of Children with Inflammatory Bowel Disease

Canadian Journal of Gastroenterology, 1990
The occurrence of natural killer cells and large granular lymphocytes (LGL) within the epithelium of colonic mucosa in children with inflammatory bowel disease (IBD) was compared to normal controls.
F Hadziselimovic, LR Emmons, U Schaub
doaj   +1 more source

Features of the subpopulation composition of circulating NK and NKT cells in patients with subclinical atherosclerosis of lower limb arteries

Атеросклероз, 2020
Aim of the study was to investigate the features of the subpopulation composition of circulating NK and NKT cells and their diagnostic value in middle-aged patients, depending on the presence of subclinical atherosclerosis of lower limb arteries ...
V. V. Genkel, I. I. Dolgushin, I. L. Baturina, I. V. Emelyanov, A. Yu. Savochkina, I. I. Shaposhnik   +5 more
doaj   +1 more source