Results 91 to 100 of about 836,642 (337)
Correction to: Killing spinor-valued forms and their integrability conditions [PDF]
, 2021 Petr Somberg, Petr Zima
openalex +1 more source
Killing Spinors for the Bosonic String
, 2011 We obtain the effective action for the bosonic string with arbitrary Yang-Mills fields, up to the \alpha' order, in general dimensions. The form of the action is determined by the requirement that the action admit well-defined Killing spinor equations ...
H. Lü +3 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The Pathogen
mBio, 2014 The fungal pathogen Candida albicans causes macrophage death and escapes, but the molecular mechanisms remained unknown. Here we used live-cell imaging to monitor the interaction of C. albicans with macrophages and show that C. albicans kills macrophages
Nathalie Uwamahoro +10 more
doaj +1 more source
TCFHs, IIB warped AdS backgrounds and hidden symmetries
Journal of High Energy Physics, 2023 We present the twisted covariant form hierarchies (TCFHs) on the internal spaces of all type IIB warped AdS backgrounds. As a result we demonstrate that the form bilinears on the internal spaces satisfy a generalisation of the conformal Killing-Yano ...
L. Grimanellis, G. Papadopoulos
doaj +1 more source
Dirty black holes: Symmetries at stationary non-static horizons
, 2004 We establish that the Einstein tensor takes on a highly symmetric form near the Killing horizon of any stationary but non-static (and non-extremal) black hole spacetime.
Martin, Damien +2 more
core +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Asian Pacific Journal of Cancer Biology, 2017 Objective: In this study, the effect of archaeosomal paclitaxel drug on breast cancer MDA-MB231 cell lines was evaluated. Material and method: The experiments were conducted to assess the cytotoxicity of paclitaxel in free form and compare it with ...
Maral Mazloumi Tabrizi +3 more
doaj +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
FEBS Open Bio, EarlyView.The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source