Results 91 to 100 of about 463,478 (294)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Killing vector fields of locally rotationally symmetric Bianchi type V spacetime

open access: yesScientific Reports
The classification of locally rotationally symmetric Bianchi type V spacetime based on its killing vector fields is presented in this paper using an algebraic method.
Shakeel Ahmad   +4 more
doaj   +1 more source

Synthesis of Paclitaxel Loaded on Nanoparticles of Archaeosomes and Investigation of Its Anti-cancer Properties

open access: yesAsian Pacific Journal of Cancer Biology, 2017
Objective: In this study, the effect of archaeosomal paclitaxel drug on breast cancer MDA-MB231 cell lines was evaluated. Material and method: The experiments were conducted to assess the cytotoxicity of paclitaxel in free form and compare it with ...
Maral Mazloumi Tabrizi   +3 more
doaj   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

TCFHs, IIB warped AdS backgrounds and hidden symmetries

open access: yesJournal of High Energy Physics, 2023
We present the twisted covariant form hierarchies (TCFHs) on the internal spaces of all type IIB warped AdS backgrounds. As a result we demonstrate that the form bilinears on the internal spaces satisfy a generalisation of the conformal Killing-Yano ...
L. Grimanellis, G. Papadopoulos
doaj   +1 more source

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Progress for the development of antibacterial surface based on surface modification technology

open access: yesSupramolecular Materials, 2022
With the increasing requirement for antibacterial surface especially in biomedical apparatus, constructing the new material surface with bactericidal activity for combating the infection caused by multi-resistant microbials possesses great significance ...
Lin Huang, Chuan-Jun Liu
doaj  

Conformal Killing forms on nearly Kähler manifolds [PDF]

open access: yesarXiv, 2019
We study conformal Killing forms on compact 6-dimensional nearly K\"ahler manifolds. Our main result concerns forms of degree 3. Here we give a classification showing that all conformal Killing 3-forms are linear combinations of $d \omega$ and its Hodge dual $* d\omega$ where $\omega$ is the fundamental 2-form of the nearly K\"ahler structure.
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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