Results 91 to 100 of about 846,182 (334)
Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing. [PDF]
PLoS Pathogens, 2018 In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease that is often difficult to treat. Exactly how immune mechanisms control A. fumigatus in immunocompetent individuals remains unclear. Here, we use transparent zebrafish
Emily E Rosowski +5 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Killing vector fields of locally rotationally symmetric Bianchi type V spacetime
Scientific ReportsThe classification of locally rotationally symmetric Bianchi type V spacetime based on its killing vector fields is presented in this paper using an algebraic method.
Shakeel Ahmad +4 more
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Correction to: Killing spinor-valued forms and their integrability conditions [PDF]
, 2021 Petr Somberg, Petr Zima
openalex +1 more source
Parallel-propagated frame along null geodesics in higher-dimensional black hole spacetimes
, 2008 In [arXiv:0803.3259] the equations describing the parallel transport of orthonormal frames along timelike (spacelike) geodesics in a spacetime admitting a non-degenerate principal conformal Killing-Yano 2-form h were solved.
B. Carter +8 more
core +1 more source
Normal Conformal Killing Forms
, 2004 We introduce in this paper normal twistor equations for differential forms and study their solutions, the so-called normal conformal Killing forms. The twistor equations arise naturally from the canonical normal Cartan connection of conformal geometry. Reductions of its holonomy are related to solutions of the normal twistor equations.
openaire +2 more sources
Transverse conformal Killing forms on Kähler foliations
Journal of Geometry and Physics, 2015 On a closed, connected Riemannian manifold with a K hler foliation of codimension $q=2m$, any transverse Killing $r\ (\geq 2)$-form is parallel (S. D. Jung and M. J. Jung [\ref{JJ2}], Bull. Korean Math. Soc. 49 (2012)). In this paper, we study transverse conformal Killing forms on K hler foliations and prove that if the foliation is minimal, then for
openaire +3 more sources
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Komar charge of N $$ \mathcal{N} $$ = 2 supergravity and its superspace generalization
Journal of High Energy PhysicsWe find the defining equations for a Killing vector and its superpartner (called the generalized Killing spinor) and use them to construct the generalized Komar superform of minimal N $$ \mathcal{N} $$ = 2 d = 4 supergravity using the superspace ...
Igor Bandos +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source