Results 221 to 230 of about 836,642 (337)

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

Advanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal, Sandra Clara‐Trujillo, Elena Lucena‐Sánchez, Francisco J. Hicke, Andrea Escudero, Sandra Pradana‐López, Nelia Jiménez‐Alduan, Paula Díez, Alba García‐Fernández, Ramón Martínez‐Máñez   +9 more
wiley   +1 more source

Categorizing immunotherapy resistance mechanisms in non-small cell lung cancer: how can we perform better? [PDF]

J Immunother Cancer
van der Geest D, van Vliet A, Peeper DS, Haanen JBAG, Smit EF, Theelen WSME.   +5 more
europepmc   +1 more source

Impaired Natural Killing of MHC Class I-Deficient Targets by NK Cells Expressing a Catalytically Inactive Form of SHP-1

, 2000
Bente Lowin-Kropf, Béatrice Kunz, Friedrich Beermann, Werner Held   +3 more
openalex   +2 more sources

An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide

Advanced Materials, EarlyView.
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon, Charles T. Osborne, Ke Wang, Rachel E. Detwiler, Konrad Meister, Jessica R. Kramer   +5 more
wiley   +1 more source

Immunization with the M12-N, M12-C, and M12-N+C fusion peptides derived from the M12 protein elicited varying levels of protective immune responses against multiple serotypes of group A <i>Streptococcus</i>. [PDF]

Front Immunol
Zhang X, Ma Y, Na R, Hou W, Hanski E, Zhou Q.   +5 more
europepmc   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

Advanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier, Byeong‐Ui Moon, Mojra Janta‐Polczynski, Yonatan Morocz, Fabian Svahn, Molly Shen, Ljuboje Lukic, Lidija Malic, Teodor Veres, Andy Ng, David Juncker   +10 more
wiley   +1 more source

CD16A Shedding Regulates Innate Cell Engager-Induced Serial Killing by Natural Killer Cells. [PDF]

Eur J Immunol
Zambarda C, Guldevall K, Breunig C, Toullec D, Sandoz PA, Carannante V, Xu S, Ross P, Kuhnigk K, Sandström N, Fontana J, Wingert S, Pinto S, Knoch J, Hussain A, Wagner AK, Pahl J, Alici E, Koch J, Önfelt B.   +19 more
europepmc   +1 more source

A Drone Manifesto: Re-forming the Partial Politics of Targeted Killing

, 2016
Katherine Chandler
openalex   +1 more source

Higher-dimensional lifts of Killing–Yano forms with torsion [PDF]

, 2016
David D. K. Chow
openalex   +1 more source

Virus Enhanced Microrobots for Biofilm Eradication

Advanced Materials, EarlyView.
Biofilms resist antimicrobials across medicine, industry, and environments. We present virus‐conjugated microrobots synthesized hydrothermally and magnetically actuated. Their motion and viral specificity enable targeted binding, penetration, and delivery, outperforming bare microrobots.
Jyoti, Sagar Arya, Xia Peng, Martin Pumera   +3 more
wiley   +1 more source