Results 71 to 80 of about 836,642 (337)

Pseudo-Killing Spinors, Pseudo-supersymmetric p-branes, Bubbling and Less-bubbling AdS Spaces

, 2011
We consider Einstein gravity coupled to an n-form field strength in D dimensions. Such a theory cannot be supersymmetrized in general, we nevertheless propose a pseudo-Killing spinor equation and show that the AdS X Sphere vacua have the maximum number ...
AA Tseytlin, B Chen, D Berenstein, E Witten, G Papadopoulos, H Lin, H Lü, H Lü, H Lü, H Lü, H. Lü, J Grover, J Grover, J Perz, JB Gutowski, JM Figueroa-O’Farrill, JM Maldacena, JP Gauntlett, JP Gauntlett, JP Gauntlett, JT Liu, K Skenderis, R Güven, S Corley, S Cucu, SS Gubser, U Gran, Zhao-Long Wang   +27 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

On a chain of reproducing kernel Cartan subalgebras

Moroccan Journal of Pure and Applied Analysis, 2021
Let 𝔤 be a semisimple Lie algebra, j a Cartan subalgebra of 𝔤, j*, the dual of j, jv the bidual of j and B(., .) the restriction to j of the Killing form of 𝔤.
Kraidi Anoh Yannick, Kangni Kinvi
doaj   +1 more source

A Novel Peptide-MHC Targeted Chimeric Antigen Receptor T Cell Forms a T Cell-like Immune Synapse

Biomedicines, 2021
Chimeric Antigen Receptor (CAR) T cell therapy is a promising form of adoptive cell therapy that re-engineers patient-derived T cells to express a hybrid receptor specific to a tumour-specific antigen of choice.
Stacie Shiqi Wang, Kylie Luong, Fiona Margaret Gracey, Shereen Jabar, Brad McColl, Ryan Stanley Cross, Misty Rayna Jenkins   +6 more
doaj   +1 more source

Uniqueness of M-theory PP-Wave Background with Extra Supersymmetries

, 2003
We examine Killing spinor equations of the general eleven-dimensional pp-wave backgrounds, which contain a scalar H(x^m,x^-) in the metric and a three-form \xi(x^m,x^-) in the flux.
C.M. Hull, D. Berenstein, D. Brecher, E. Lozano-Tellechea, E.G. Gimon, H. Lu, H. Singh, I. Bena, J. Figueroa-O’Farrill, J. Figueroa-O’Farrill, J. Kowalski-Glikman, J. Kowalski-Glikman, J. Michelson, J. Michelson, J.M. Figueroa-O’Farrill, J.P. Gauntlett, J.P. Gauntlett, K. Sugiyama, M. Blau, M. Blau, M. Blau, M. Blau, M. Cvetic, M. Cvetic, M. Hatsuda, M. Hatsuda, M. Sakaguchi, Makoto Sakaguchi, Nobuyoshi Ohta, P. Meessen, P.T. Chrusciel, R. Corrado, R. Gueven, R.R. Metsaev, S.j. Hyun, T. Ortin   +35 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Supersymmetry of the Robinson-Trautman solution

Journal of High Energy Physics
The Robinson-Trautman solution in the Einstein-Maxwell-Λ system admits a shear-free and twist-free null geodesic congruence with a nonvanishing expansion.
Masato Nozawa
doaj   +1 more source

7D supersymmetric Yang-Mills on curved manifolds

Journal of High Energy Physics, 2017
We study 7D maximally supersymmetric Yang-Mills theory on curved manifolds that admit Killing spinors. If the manifold admits at least two Killing spinors (Sasaki-Einstein manifolds) we are able to rewrite the supersymmetric theory in terms of a ...
Konstantina Polydorou, Andreas Rocén, Maxim Zabzine   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source