Results 81 to 90 of about 463,478 (294)

7D supersymmetric Yang-Mills on curved manifolds

Journal of High Energy Physics, 2017
We study 7D maximally supersymmetric Yang-Mills theory on curved manifolds that admit Killing spinors. If the manifold admits at least two Killing spinors (Sasaki-Einstein manifolds) we are able to rewrite the supersymmetric theory in terms of a ...
Konstantina Polydorou, Andreas Rocén, Maxim Zabzine   +2 more
doaj   +1 more source

Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing. [PDF]

PLoS Pathogens, 2018
In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease that is often difficult to treat. Exactly how immune mechanisms control A. fumigatus in immunocompetent individuals remains unclear. Here, we use transparent zebrafish
Emily E Rosowski, Nicholas Raffa, Benjamin P Knox, Netta Golenberg, Nancy P Keller, Anna Huttenlocher   +5 more
doaj   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Supersymmetry of the Robinson-Trautman solution

Journal of High Energy Physics
The Robinson-Trautman solution in the Einstein-Maxwell-Λ system admits a shear-free and twist-free null geodesic congruence with a nonvanishing expansion.
Masato Nozawa
doaj   +1 more source

Well Killing Technology before Workover Operation in Complicated Conditions

Energies, 2021
Well killing is an important technological stage before conducting workover operation, one of the tasks of which is to preserve and restore the natural filtration characteristics of the bottomhole formation zone (BFZ). Special attention should be paid to
Dmitry V. Mardashov, Mikhail K. Rogachev, Yury V. Zeigman, Vyacheslav V. Mukhametshin   +3 more
doaj   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages

mBio, 2014
The fungal pathogen Candida albicans causes macrophage death and escapes, but the molecular mechanisms remained unknown. Here we used live-cell imaging to monitor the interaction of C. albicans with macrophages and show that C. albicans kills macrophages
Nathalie Uwamahoro, Jiyoti Verma-Gaur, Hsin-Hui Shen, Yue Qu, Rowena Lewis, Jingxiong Lu, Keith Bambery, Seth L. Masters, James E. Vince, Thomas Naderer, Ana Traven   +10 more
doaj   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Gauging generalised symmetries in linear gravity

Journal of High Energy Physics
The theory of a free spin-2 field on Minkowski spacetime has 1-form and (d − 3)-form symmetries associated with conserved currents formed by contractions of the linearised Riemann tensor with conformal Killing-Yano 2-forms. We show that a subset of these
Chris Hull, Maxwell L. Hutt, Ulf Lindström   +2 more
doaj   +1 more source

Second Chern-Einstein metrics on four-dimensional almost-Hermitian manifolds

Complex Manifolds, 2023
We study four-dimensional second Chern-Einstein almost-Hermitian manifolds. In the compact case, we observe that under a certain hypothesis, the Riemannian dual of the Lee form is a Killing vector field.
Barbaro Giuseppe, Lejmi Mehdi
doaj   +1 more source