Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang +11 more
wiley +1 more source
On the structure vector field of a real hypersurface in complex two-plane Grassmannians
Machado Carlos, Pérez Juan
doaj +1 more source
Oncostatin-M ligand-based CAR-T therapy displays robust anti-tumor activity against osteosarcoma. [PDF]
Feinberg D +15 more
europepmc +1 more source
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan +9 more
wiley +1 more source
Natural genetic variation impacts complement inhibitory activity of PFam54 orthologs of Asian Borrelia bavariensis. [PDF]
Langhoff L +11 more
europepmc +1 more source
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar +10 more
wiley +1 more source
Insecticide-treated screening of windows for household protection against insecticide-resistant Anopheles gambiae sensu lato in Côte d'Ivoire: a semi-field trial. [PDF]
Zoh MG +9 more
europepmc +1 more source
ABSTRACT Background The association of chloride intracellular channel 2 (CLIC2) with tumors has remained unclear. However, recently, CLIC2 was found to exhibit antitumor properties in some tumors. In this study, we aimed to evaluate the clinical relevance of CLIC2 expression in head and neck squamous cell carcinoma (HNSCC) to determine whether it ...
Yuki Hosokawa +9 more
wiley +1 more source
Cascades of effectiveness of next-generation insecticide-treated nets against malaria, from entomological trials to real-life conditions. [PDF]
Champagne C +18 more
europepmc +1 more source
Chlorfenapyr bednets effectively overcome pyrethroid resistance escalation in highly resistant Anopheles malaria vectors in Uganda. [PDF]
Oruni A +8 more
europepmc +1 more source

