Results 161 to 170 of about 129,718 (286)

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

open access: yesExploration, EarlyView.
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang   +11 more
wiley   +1 more source

Oncostatin-M ligand-based CAR-T therapy displays robust anti-tumor activity against osteosarcoma. [PDF]

open access: yesBMC Med
Feinberg D   +15 more
europepmc   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

open access: yesFlavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan   +9 more
wiley   +1 more source

Natural genetic variation impacts complement inhibitory activity of PFam54 orthologs of Asian Borrelia bavariensis. [PDF]

open access: yesSci Rep
Langhoff L   +11 more
europepmc   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

open access: yesFood Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar   +10 more
wiley   +1 more source

Insecticide-treated screening of windows for household protection against insecticide-resistant Anopheles gambiae sensu lato in Côte d'Ivoire: a semi-field trial. [PDF]

open access: yesParasit Vectors
Zoh MG   +9 more
europepmc   +1 more source

Chloride Intracellular Channel 2 Can Function as a Malignant Factor in Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The association of chloride intracellular channel 2 (CLIC2) with tumors has remained unclear. However, recently, CLIC2 was found to exhibit antitumor properties in some tumors. In this study, we aimed to evaluate the clinical relevance of CLIC2 expression in head and neck squamous cell carcinoma (HNSCC) to determine whether it ...
Yuki Hosokawa   +9 more
wiley   +1 more source

Cascades of effectiveness of next-generation insecticide-treated nets against malaria, from entomological trials to real-life conditions. [PDF]

open access: yesNat Commun
Champagne C   +18 more
europepmc   +1 more source

Chlorfenapyr bednets effectively overcome pyrethroid resistance escalation in highly resistant Anopheles malaria vectors in Uganda. [PDF]

open access: yesSci Rep
Oruni A   +8 more
europepmc   +1 more source

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