Results 71 to 80 of about 129,718 (286)

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

open access: yesAdvanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon   +6 more
wiley   +1 more source

Projective Vector Fields on Semi-Riemannian Manifolds

open access: yesMathematics
This paper explores the properties of projective vector fields on semi-Riemannian manifolds. The main result establishes that if a projective vector field P on such a manifold is also a conformal vector field with potential function ψ and the vector ...
Norah Alshehri, Mohammed Guediri
doaj   +1 more source

Effective field theory for non-relativistic hydrodynamics

open access: yesJournal of High Energy Physics, 2020
We write down a Schwinger-Keldysh effective field theory for non-relativistic (Galilean) hydrodynamics. We use the null background construction to covariantly couple Galilean field theories to a set of background sources.
Akash Jain
doaj   +1 more source

Locally inertial null normal coordinates

open access: yes, 2012
Locally inertial coordinates are constructed by carrying Riemann normal coordinates on a codimension two spacelike surface along the geodesics normal to it.
Guedens, Raf
core   +1 more source

On Killing vector fields and Newman–Penrose constants [PDF]

open access: yesJournal of Mathematical Physics, 2000
Asymptotically flat space–times with one Killing vector field are studied. The Killing equations are solved asymptotically using polyhomogeneous expansions (i.e., series in powers of 1/r and ln r), and solved order by order. The solution to the leading terms of these expansions yields the asymptotic form of the Killing vector field.
openaire   +3 more sources

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

open access: yesAdvanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi   +12 more
wiley   +1 more source

A generalization and short proof of a theorem of Hano on affine vector fields [PDF]

open access: yes, 2016
We prove that a bounded affine vector field on a complete Finsler manifold is a Killing vector field. This generalizes the analogous result of Hano for Riemannian manifolds.
Kertesz, David Csaba   +3 more
core   +2 more sources

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

open access: yesAdvanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo   +15 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Exactly solvable strings in Minkowski spacetime

open access: yes, 2010
We study the integrability of the equations of motion for the Nambu-Goto strings with a cohomogeneity-one symmetry in Minkowski spacetime. A cohomogeneity-one string has a world surface which is tangent to a Killing vector field. By virtue of the Killing
Burden C J   +10 more
core   +1 more source

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