Results 251 to 260 of about 2,607,457 (313)

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

The Role of Protein Kinases in the Management of Oncological Diseases by Acting on Ferroptotic Pathways. [PDF]

Int J Mol Sci
Folgiero V, Caforio M.
europepmc   +1 more source

Identification of a New Phosphorylated Host Interactor of the Epstein-Barr Virus (EBV) Kinase BGLF4 Suggests Key Points for EBV-Specific Antiviral Drug Targeting. [PDF]

Int J Mol Sci
Kögler M, Wangen C, Hammerschmitt A, Obergfäll D, Hahn F, Marschall M.   +5 more
europepmc   +1 more source

Epigenetic Regulation of Trk Receptors and Neurotrophic Signalling in Neuroblastoma: Mechanisms, Plasticity, and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Siddi C, Balla J, Fadda P, Dedoni S.
europepmc   +1 more source

A different MAPK, ERK5 plays a critical role in cell specification and differentiation. [PDF]

Biochem Biophys Rep
Li J, Hou X, Li X, Ji S.
europepmc   +1 more source

IQDMA disrupts STAT5 nuclear transport through CDC42-PAK2 axis collapse in cutaneous T-cell lymphoma. [PDF]

Front Immunol
Dey S, Sorger H, Schlederer M, Perchthaler I, Metzelder M, Kenner L, Moriggl R, Wolf P.   +7 more
europepmc   +1 more source

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats. [PDF]

Int J Mol Med
Song H, Gao D.
europepmc   +1 more source

IRAK4 autophosphorylation functions as a molecular switch to regulate death domain assembly and Myddosome maturation

Taylor M, Srikanth N, Deliz-Aguirre R, Gola DK, Bilay M, Ziska E, Kelsall I, Kukathu Y.   +7 more
europepmc   +1 more source