Results 191 to 200 of about 5,216 (259)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Programmable Porosity in Polymers via Microfluidic Templating and 3D Printing

open access: yesSmall Methods, EarlyView.
Fluid templating is a powerful way to produce porous polymers. Microfluidic technologies enable fine control over the dimension and packing of bubbles and droplets. Combined with additive manufacturing, microfluidic templating enables the creation of polymeric functionally graded porous materials in which both porosity and three‐dimensional geometry ...
Federico Serpe   +3 more
wiley   +1 more source

A 4D‐STEM Tomographic Framework Assisted by Object Tracking for Nanoparticle Structure Determination

open access: yesSmall Methods, EarlyView.
4D‐STEM tomography is used as a new methodology for 3D ED data acquisition to solve structures. Object tracking and segmentation methods are applied for the extraction of 3D ED datasets from regions of interest in a 4D‐STEM tomogram. Owing to its nanometric resolution, 4D‐STEM tomography can tackle challenging samples being too small for 3D ED, have ...
Saleh Gholam   +8 more
wiley   +1 more source

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