Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Background Duchenne muscular dystrophy (DMD) is a severe, life‐limiting neuromuscular disorder (NMD) characterized by progressive muscle wasting and mitochondrial dysfunction. Although gene therapies offer promise, even those already approved by regulatory agencies, their use remains constrained by mutation specificity, delivery challenges and
Sean Y. Ng +12 more
wiley +1 more source
Maximal eccentric-concentric strength determines stretch-shortening cycle leg power across biological sexes. [PDF]
Sci RepJordan MJ +5 more
europepmc +1 more source
Elevating Circulating L‐Kynurenine Promotes Frailty in Aging Mice
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Background L‐Kynurenine (L‐Kyn), a product of tryptophan catabolism, increases with age and has been associated with reduced physical function and increased frailty in humans. Robustly expressed in skeletal muscle, kynurenine aminotransferases (KATs) degrade L‐Kyn into kynurenic acid and are regulated by the transcriptional co‐regulator ...
Mia Y. Kawaida +8 more
wiley +1 more source
Role of Acid‐Sensing Ion Channels 1a in the Regulation of Obesity and the Gut Microbiota
Obesity, Volume 34, Issue 2, Page 372-381, February 2026.ABSTRACT Objective Acid‐sensing ion channels are proton‐activated ion channels predominantly found in the nervous system. They are well known to affect metabolic and neurological health, yet their role in obesity and gut physiology remains unclear. This study investigates how systemic deletion of Asic1a influences obesity, metabolic, and gut‐based ...
Jane Shearer +7 more
wiley +1 more source
α-Klotho Supplementation Mitigates Cumulative Exercise-Induced Fatigue via Coordinated NRF2-Mediated Antioxidant Defense and AKT/GS-Driven Hepatic Glycogen Supercompensation in Mice. [PDF]
Int J Mol SciZheng L, Wang Y, Xiao Z, Rao Z, Shi R.
europepmc +1 more source
Beliefs and Behaviors Related to Physical Activity in Black Girls With Asthma
Pediatric Pulmonology, Volume 61, Issue 2, February 2026.ABSTRACT Introduction and Objective Physical activity (PA) is associated with improved asthma outcomes. Black girls face higher rates of asthma morbidity and are less likely to meet recommended PA than their White and Black male peers. To address these health disparities, it is essential to understand beliefs and behaviors related to PA among Black ...
Nora Spadoni +6 more
wiley +1 more source
Reasons for Participating in the EDS-HEART Program: Holistic and Performative Within a Supportive Community. [PDF]
Int J Environ Res Public HealthKosma M +3 more
europepmc +1 more source
Frequency Band Analysis of Multiple Stationary Time Series
Statistics in Medicine, Volume 45, Issue 3-5, February 2026.ABSTRACT The frequency‐domain properties of biomedical signals offer valuable insights into health and functioning of underlying physiological systems. The power spectrum, which characterizes these properties, is often summarized by partitioning frequencies into standard bands and averaging power within bands.
Connor K. Brubaker +3 more
wiley +1 more source
Editorial: A Step-by-step Statistical Decision Framework for a Gender-inclusive Approach in Sport and Exercise Science Research. [PDF]
Int J Exerc SciNavalta JW +3 more
europepmc +1 more source