Results 81 to 90 of about 1,442,079 (261)

Kinetics of chemical processes

, 1991
Kinetics of Chemical Processes details the concepts associated with the kinetic study of the chemical processes.
Boudart, Michel
core  

Institute for Sport Coaching

, 2016
The Institute for Sport Coaching is a not-for-profit organization devoted to the creation and delivery of educational experiences and leadership tools to sport coaches. Based in Acton, Massachusetts, USA, the Institute’s mission is to provide excellence
Dorsch, Travis E., Bolter, Nicole D.
core   +1 more source

Modeling the stance leg in two-dimensional analyses of sprinting: inclusion of the MTP joint affects joint kinetics. [PDF]

, 2012
Two-dimensional analyses of sprint kinetics are commonly undertaken but often ignore the metatarsalphalangeal (MTP) joint and model the foot as a single segment.
Salo, Aki I. T., Bezodis, Neil E., Salo, Aki I.T., Bezodis, Neil E, Trewartha, Grant; id_orcid, Salo, Aki I T, Trewartha, Grant   +6 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Causal network inference using biochemical kinetics [PDF]

, 2014
Motivation: Networks are widely used as structural summaries of biochemical systems. Statistical estimation of networks is usually based on linear or discrete models.
Bayani, Nora, Mukherjee, Sach, Dondelinger, Frank, Bayani, N, Korkola, J, Dondelinger, F, Mukherjee, S, Oates, Chris J., Gray, JW, Korkola, James, Gray, Joe W., Oates, CJ   +11 more
core   +1 more source

Musculoskeletal Injuries, Exercise Behaviors, and Reproductive Health Are Related to Physical Fitness of Female First-Responders and Health Care Providers

Women's Health Reports
Introduction: Musculoskeletal injuries (MSKi) are the most common injury type experienced by first-responders and health care providers (HCPs), making them a significant threat to physical and mental well-being.
C. M. Edwards, J. L. Puranda, É. Miller, M. Aboudlal, N. O’Rourke, M. L. MacDonald, K. B. Adamo   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Kinetics of Struvite Precipitation: Effect of the Magnesium Dose on Induction Times and Precipitation Rates [PDF]

, 2007
The presence of white deposits in specific areas of wastewater treatment plants is generally the consequence of the spontaneous formation of a mineral called struvite.
Hobbs, Phil, Parsons, Simon A., Le Corre, Kristell S., Valsami-Jones, Eugenia   +3 more
core   +1 more source