Results 81 to 90 of about 1,262,165 (318)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
An investigation into the behaviour, kinetics & mechanisms involved in the precipitation of a moderately soluble system [PDF]
This dissertation consists of three interrelated sections dealing with: (i) Development of a suitable seed preparation technique, (ii) Determination of growth and aggregation kinetics and (iii) Determination of the induction ...
Musil, Emily Ann
core
“Kinetic” and “Transmutation” [PDF]
I. WHEN, in 1864, I wrote for the Reader the history of the Baconian Philosophy of Heat, I found in use, in connection with the subject, the term “dynamical theory of heat,” in English, which was employed as an equivalent for the expression “mechanische Warmetheorie,” current in German.
openaire +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Flame Speciation and Laminar Burning Velocity of Tetralin Flames Under Atmospheric Pressure
We present a combined experimental and modeling study of premixed atmospheric-pressure tetralin flames. Chemical speciation in near-stoichiometric (φ = 0.8–1.0) tetralin/O2/Ar flames was characterized by probe-sampling molecular-beam mass spectrometry ...
Vladislav V. Matyushkov +7 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Kinetics of the Hematite to Magnetite Reduction in H2-H2O, H2-H2O-N2 Mixtures [PDF]
The kinetics of the hematite to rnagnetite reduction have been studied in H2-H2O, and H2-H2O-N2 gas mixtures, using natural as well as synthetic specimens. The reactivity of hematite was found to be related to the structural defects formed during the
Nabi, Ghulam
core
Causal network inference using biochemical kinetics [PDF]
Motivation: Networks are widely used as structural summaries of biochemical systems. Statistical estimation of networks is usually based on linear or discrete models.
Bayani, Nora +11 more
core +1 more source
Background Mobile technology is ubiquitous. Women of childbearing age have embraced health information technology for pregnancy-related counsel as prenatal care provider communication is increasingly scarce and brief. Pregnant women and new mothers place
Lyra Halili +5 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

