Results 71 to 80 of about 6,177,002 (392)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Microbial Volatiles: Small Molecules with an Important Role in Intra- and Inter-Kingdom Interactions
Frontiers in Microbiology, 2017 During the last decades, research on the function of volatile organic compounds focused primarily on the interactions between plants and insects. However, microorganisms can also release a plethora of volatiles and it appears that microbial volatile ...
Kristin Schulz-Bohm +2 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
China's Forgotten Kingdom - Exhibition Catalogue [PDF]
, 2013 Exhibition catalogue for 'China's Forgotten Kingdom', a touring exhibition of work focusing on the visual identity of the Naxi ethnic minority people from Yunnan province in ...
core
Jamaan at the pass of Bi’rein. An Iron Age IIB-C Ammonite stronghold in central Jordan [PDF]
, 2016 In years 2015-2016 the Zarqa Directorate of the Department of Antiquities of the Hashemite Kingdom of Jordan carried out a rescue excavation at the site of Jamaan, an Iron Age IIB-C Ammonite stronghold 16 Km north of ‘Amman.
Gharib, Romeel, Nigro, Lorenzo
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Towards a Mixed Economy of Youth Justice [PDF]
, 2010 The concept of a ?mixed economy of justice? involves the idea that welfare is delivered by a range of agencies working in partnership. The United Kingdom 1998 Crime and Disorder Act introduced multi-agency approaches requiring criminal justice agencies ...
Cox, P
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Pitcairn Islands The world's Largest Fully Protected Marine Reserve [PDF]
, 2015 In March 2015, the United Kingdom declared the world's largest fully protected marine reserve in the remote waters surrounding the Pitcairn Islands in the South Pacific Ocean. The designation marks the first time any government has combined creation of a
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source