Results 51 to 60 of about 5,829,655 (310)
Jamaan at the pass of Bi’rein. An Iron Age IIB-C Ammonite stronghold in central Jordan [PDF]
, 2016 In years 2015-2016 the Zarqa Directorate of the Department of Antiquities of the Hashemite Kingdom of Jordan carried out a rescue excavation at the site of Jamaan, an Iron Age IIB-C Ammonite stronghold 16 Km north of ‘Amman.
Gharib, Romeel, Nigro, Lorenzo
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Promoting family medicine [PDF]
, 2007 The year 2002 saw the publication of a landmark white paper in the United Kingdom entitled "Shifting the balance." It proposed redistribution of funds with the lion's share of the NHS budget going towards Primary Care services.
Abela, Jurgen C.
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
THE AESTHETIC OF THE DALANG JANGGA IN THE STORY OF CUPAK WENT TO HEAVEN [PDF]
, 2003 Aesthetic ideology ‘behind the palace centric aesthetic poet memberontaki still using elemens such as language shadow puppet show, sight, sound and motion.
I Nyoman, Murtana
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Matthew 5:17 and Matthew's Community
HTS Teologiese Studies/Theological Studies, 2016 One of the central arguments in establishing the ‘Christian-Jewish’ nature of the Matthean community is the argument that Matthew’s community was law observant.
Bradley Trout
doaj +1 more source
A European union and Canadian review of public health nursing preparation and practice. [PDF]
, 2013 This study explores the preparation and role of the public health nurse (PHN) across European Union (EU) countries (Finland, Sweden, and the United Kingdom) and Canadian provinces (Alberta, New Brunswick, and Prince Edward Island)
Battle Haugh +37 more
core +1 more source