Results 41 to 50 of about 3,195,937 (263)

BHATTARA NARAPATI

open access: yesBerkala Arkeologi, 1985
Sejarah Majapahit setelah meninggalnya raja Hayam Wuruk sekitar tahun 1389, diwarnai dengan bermacam-macam peristiwa pertikaian di kalangan keluarga kerajaan. Pertikaian tersebut bersumber pada masalah perebutan tahta pemerintahan di antara para penguasa
Soeroso
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Nação

open access: yesLer História, 2008
The concept of nation has undergone a profound change between 1750 and 1850, only understandable in the context of historical changes that occurred following the French invasion.
Sérgio Campos Matos
doaj   +1 more source

The Ratu Boko Mantra And The Sailendras

open access: yesBerkala Arkeologi, 2004
The Ratu Boko (or Ratu Baka) plateau, near Yogyakarta in southern central Java, is surrounded by an impressive array of Hindu and Buddhist shrines.
Roy Jordaan, Brian Colless
doaj   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

الزخارف الحيوانية علي الفخار في الدولة الحديثة [PDF]

open access: yesمجلة کلية الآداب. جامعة أسوان
تعود أهمية الزخارف المتنوعة علي الفخار في معرفة تفاصيل حياة المجتمعات ومظهراً للتقدم ومدي الذوق الفني أنذاك وتطور الفن خلال تلك القترة المصاحبة لظهوره, ونستنبط من موضوعات الزخرفة علي الفخار العادات الإجتماعية , والحياة الدينية , والمعبودات وممارسة الطقوس
عزت رجب عبد الله ابوطالب
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Incomplete Penetrance and Variable Expressivity: From Clinical Studies to Population Cohorts

open access: yesFrontiers in Genetics, 2022
The same genetic variant found in different individuals can cause a range of diverse phenotypes, from no discernible clinical phenotype to severe disease, even among related individuals.
Rebecca Kingdom, Caroline F. Wright
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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