Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion
Advanced Science, 2020 Medical technologies from physics are imperative in the diagnosis and therapy of many types of diseases. In 2013, a novel cold physical plasma treatment concept was accredited for clinical therapy.
Sander Bekeschus +5 more
doaj +1 more source
Frontiers in Physics, 2020 The requirements for new technologies to serve as anticancer agents go far beyond their toxicity potential. Novel applications also need to be safe on a molecular and patient level.
Eric Freund +13 more
doaj +1 more source
Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
MedComm, Volume 7, Issue 4, April 2026.Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
Move beyond free radical theory of aging
iMetaOmics, Volume 3, Issue 1, March 2026.Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley +1 more source
The antioxidant potential in blood plasma.
, 2016 Chicken blood plasma was collected after cold plasma treatment, and the antioxidant potential (AOP) was measured by means of assessing the total ascorbic acid equivalents that have not been oxidized by the sample.
Axel Sckell (14514) +7 more
core +1 more source
Genotoxitätsuntersuchung von atmosphärischem Niedertemperaturplasma anhand des Micronucleustests am angebrüteten Hühnerei [PDF]
, 2016 Für den zukünftigen Einsatz von Niedertemperaturplasma in Bereichen der Medizin müssen potentielle genotoxische Risiken von Plasma ausgeschlossen werden.
Kluge, Susanne
core +1 more source
Platelets are key in cold physical plasma-facilitated blood coagulation in mice [PDF]
, 2017 Purpose: Surgical interventions inevitably lead to destruction of blood vessels. This is especially dangerous in anticoagulated patients. Electrocauterization is a frequently used technique to seal incised tissue.
Bekeschus, Sander +5 more
core +1 more source
Induktion von Apoptose durch kaltes physikalisches Plasma – molekulare und zelluläre Analyse in einem in vitro Osteosarkom-Modell [PDF]
, 2023 Seit Einführung der multimodalen Chemotherapie vor über 30 Jahren liegt die 5- Jahres-Überlebensrate des Osteosarkoms (OS) unverändert bei ca. 70 %. Als potentielle neue Therapieoption ruft kaltes atmosphärisches Plasma (cold atmospheric plasma, CAP) in ...
Wien, Lasse
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Unravelling reactive oxygen species production in low temperature, atmospheric pressure plasmas [PDF]
Low temperature plasmas (LTPs) are efficient sources of reactive oxygen and nitrogen species (RONS) at atmospheric pressure. Understanding how different parameters influence RONS production is essential for optimising LTP devices for biomedical ...
Harris, Benjamin
core +4 more sources
Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo
Advanced Functional Materials, Volume 36, Issue 7, 22 January 2026.This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić +9 more
wiley +1 more source