Results 61 to 70 of about 675 (151)
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Induktion von Apoptose durch kaltes physikalisches Plasma – molekulare und zelluläre Analyse in einem in vitro Osteosarkom-Modell [PDF]
Seit Einführung der multimodalen Chemotherapie vor über 30 Jahren liegt die 5- Jahres-Überlebensrate des Osteosarkoms (OS) unverändert bei ca. 70 %. Als potentielle neue Therapieoption ruft kaltes atmosphärisches Plasma (cold atmospheric plasma, CAP) in ...
Wien, Lasse
core +1 more source
Resonances and patterns within the kINPen-MED atmospheric pressure plasma jet [PDF]
Chaos 2013 Chaotic Modeling and Simulation International Conference, At Istanbul Turkey, Volume: 1The kINPen MED atmospheric pressure plasma jet is now undergoing clinical studies that are designed to investigate its suitability as a device for use in ...
Law, Victor J. +3 more
core +1 more source
Argon Cold Plasma Modification of Polyethylene Films to Tailor Surface and Barrier Properties
Argon cold plasma treatment of low‐density polyethylene (LDPE) and high‐density polyethylene (HDPE) films induces major changes in surface chemistry and morphology. Contact angles decrease significantly while surface energy increases, improving wettability. FTIR confirms the formation of polar functional groups, while pronounced etching, roughness, and
Aikaterini Spanou +11 more
wiley +1 more source
Hydrogen peroxide concentration after plasma treatment using the kINPen (a) or COST-jet (b). Treatment with the kINPen were performed in N2 environment due to curtain gas, COST-jet was operated in open air. Triplicates (n = 3) with standard deviation are
Björn Offerhaus (6680984) +9 more
core +1 more source
Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
The antioxidant potential in blood plasma.
Chicken blood plasma was collected after cold plasma treatment, and the antioxidant potential (AOP) was measured by means of assessing the total ascorbic acid equivalents that have not been oxidized by the sample.
Axel Sckell (14514) +7 more
core +1 more source
Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion
Medical technologies from physics are imperative in the diagnosis and therapy of many types of diseases. In 2013, a novel cold physical plasma treatment concept was accredited for clinical therapy.
Sander Bekeschus +5 more
doaj +1 more source
The requirements for new technologies to serve as anticancer agents go far beyond their toxicity potential. Novel applications also need to be safe on a molecular and patient level.
Eric Freund +13 more
doaj +1 more source
Move beyond free radical theory of aging [PDF]
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Dai X, Hu M, Lyu R.
europepmc +2 more sources

