ABSTRACT Background Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients. Objective This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a ...
Timoleon Siempis +3 more
wiley +1 more source
Intestinal <i>Klebsiella pneumoniae</i> enhances neuroinflammation and seizure susceptibility in a pentylenetetrazole-induced acute seizure model. [PDF]
Li J +5 more
europepmc +1 more source
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley +1 more source
Checkerboard Insights: Diagnostic Integration of Synergy Testing for Multidrug-Resistant Klebsiella Isolates in Critical Care. [PDF]
Nautiyal G, Rawat A, Jain R, Mukim Y.
europepmc +1 more source
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop +5 more
wiley +1 more source
<i>Klebsiella pneumoniae</i> Liver Abscess in a Filipino Patient With Previously Undiagnosed Diabetes: Successful Conservative Management. [PDF]
Paz Y Mino L +3 more
europepmc +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Genomic and phenotypic characterization of Klebsiella pneumoniae phage KP Ø1: a novel lytic Slopekvirus targeting uropathogenic multidrug-resistant Klebsiella pneumoniae. [PDF]
Fadl R +7 more
europepmc +1 more source
The roles of distinct lung neutrophil compartments involved in hvKp infection remain poorly understood. Here, utilising single‐cell RNA sequencing, we identified four neutrophil subsets in the lungs of hvKp‐infected mice: N1, N2, N3a, and N3b, which were organised along a maturation trajectory.
Xiang Fang +7 more
wiley +1 more source
Characterization of resistance to last-line therapeutic molecules and genetic diversity of <i>Klebsiella</i> spp. strains involved in urinary tract infections in women: the case of Hôpital d'Instruction des Armées Omar Bongo Ondimba. [PDF]
Mayombo Ngoussou E +8 more
europepmc +1 more source

