Results 181 to 190 of about 227,483 (301)

Evolution of Bacterial Yield and Antimicrobial Resistance in Chronic Rhinosinusitis Patients in a Dedicated Sinus Centre

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Background Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients. Objective This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a ...
Timoleon Siempis   +3 more
wiley   +1 more source

Can Artificial Intelligence Be Utilised to Develop Point‐of‐Care Endodontic Microbiological Technologies?

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop   +5 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Single‐Cell Atlas Reveals Neutrophil Heterogeneity in Hypervirulent Klebsiella pneumoniae Infection‐Induced Sepsis

open access: yesImmunology, EarlyView.
The roles of distinct lung neutrophil compartments involved in hvKp infection remain poorly understood. Here, utilising single‐cell RNA sequencing, we identified four neutrophil subsets in the lungs of hvKp‐infected mice: N1, N2, N3a, and N3b, which were organised along a maturation trajectory.
Xiang Fang   +7 more
wiley   +1 more source

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