ABSTRACT The increasing issue of infections caused by methicillin‐resistant Staphylococcus aureus (MRSA) necessitates rapid and reliable diagnostic methods. While existing RPA‐CRISPR/Cas12a platforms have demonstrated potential for MRSA detection, most rely on single‐gene targets or require multiple Cas enzymes.
Lei Chen +3 more
wiley +1 more source
Erratum: Comparative in vitro Activity and Clinical Outcomes of Eravacycline, Tigecycline, and Omadacycline Against Carbapenem-Resistant <i>Acinetobacter baumannii</i> and <i>Klebsiella pneumoniae</i> [Corrigendum]. [PDF]
europepmc +1 more source
Bee sting-induced hypervirulent <i>Klebsiella pneumoniae</i> infection causing fulminant necrotizing fasciitis: case report and narrative review. [PDF]
Hu Y +12 more
europepmc +1 more source
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
Molecular detection of hypervirulent Klebsiella pneumoniae (hvKp) in Egyptian poultry. [PDF]
Ahmed ZS +3 more
europepmc +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Our pilot clinical study in laryngeal transplantation achieved divergent outcomes: two cases maintained functional speech/swallowing with around 2 year graft survival and have been ongoing, while two succumbed to sepsis (10mo) and hemorrhagic recurrence (11mo).
Zheng Jiang +9 more
wiley +1 more source
Synergistic activity of cefepime/enmetazobactam with meropenem, piperacillin, piperacillin/tazobactam, cefiderocol and fosfomycin against Klebsiella pneumoniae carrying blaKPC allelic variants. [PDF]
Crema A +3 more
europepmc +1 more source
Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between
This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha +5 more
wiley +1 more source
Early procalcitonin kinetics as an independent predictor of mortality in multi-drug resistant Klebsiella spp. bloodstream infections: a retrospective cohort study. [PDF]
Korkmaz N +11 more
europepmc +1 more source

