Results 161 to 170 of about 109,518 (258)
openaire +1 more source
ABSTRACT Background and Aims Meningitis remains a global health challenge, characterized by substantial regional and etiologic disparities. This study aimed to analyze recent trends, forecast future burden, and examine the influence of development status on meningitis outcomes.
Mehdi Azizmohammad Looha +4 more
wiley +1 more source
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) represent a unique clinical syndrome affecting up to 80% of PSC patients, characterised by distinct epidemiological patterns, pathophysiological mechanisms and clinical outcomes that differ substantially from either condition occurring independently ...
Luisa Bertin +7 more
wiley +1 more source
Hospital-Based Surveillance of <i>Klebsiella pneumoniae</i> and Other <i>Klebsiella</i> species in Southern Saudi Arabia (2012-2024): Escalating Carbapenem and DTR Resistance with Species-Specific Phenotypes and Genotypes. [PDF]
Shabi Y +12 more
europepmc +1 more source
ABSTRACT The increasing issue of infections caused by methicillin‐resistant Staphylococcus aureus (MRSA) necessitates rapid and reliable diagnostic methods. While existing RPA‐CRISPR/Cas12a platforms have demonstrated potential for MRSA detection, most rely on single‐gene targets or require multiple Cas enzymes.
Lei Chen +3 more
wiley +1 more source
Development and validation of a machine learning-based early warning model for carbapenem-resistant <i>Klebsiella pneumoniae</i> bloodstream infections using non-carbapenem susceptibility profiles. [PDF]
Song J +5 more
europepmc +1 more source
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Severe Lung Abscess and Sepsis Caused by <i>Klebsiella ozaenae</i> in a Malnourished Patient With Psychiatric Disease. [PDF]
Araya T +5 more
europepmc +1 more source

