Results 161 to 170 of about 112,576 (260)

Chemical Optimization of Temporin A–L Peptides: From Native Isoforms to Enhanced Antimicrobial Analogs

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino, Paolo Grieco, Francesco Merlino   +2 more
wiley   +1 more source

Epidemiological and Genomic Characteristics of <i>bla</i> _CTX-M and <i>bla</i> _NDM-Producing <i>K. pneumoniae</i> From Dairy Cows in Henan Province, China. [PDF]

Transbound Emerg Dis
Feng Y, Li W, Ma M, Zhai Y, Wu H, Liu J, Hu G, He D, Pan Y.   +8 more
europepmc   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite, Lucas H. S. Ocarino, Gabriel C. Veríssimo, Philipe O. Fernandes, Dara Fernanda Pereira, Fernanda Kelly M. e Oliveira, Alberto Marbán‐González, José L. Medina‐Franco, Mateus Sá M. Serafim, Thales Kronenberger, Vinícius G. Maltarollo   +10 more
wiley   +1 more source

Hypervirulent and Drug-Resistant <i>Klebsiella pneumoniae</i>: Clinical Challenges and Alternative Treatment Strategies. [PDF]

Int J Gen Med
Bani Abdel-Rahman S, Altarawneh H, Alfreahat HAH, Alhazmi KA, Alharbi OS, Gazzaz M, Alharthi TM, Ismaeel LA, Halabi WS, Sharif AT, Redwan B, Alkuwaity KK, Alhazmi W, Saleh BH, Alqarni MA, Alsaedi A, Alhussainy NH, Niyazi HA, Niyazi HA, AbdulMajed H, Juma NA, Ibrahem K.   +21 more
europepmc   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, Volume 13, Issue 44, 7 August 2026.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Epidemiological trends in antibiotic resistant Klebsiella pneumoniae in healthcare settings in Burkina Faso: a systematic review and meta-analysis. [PDF]

BMC Infect Dis
Soma D, Diarra FBJ, Diallo D, Somda NS, Garba Z, Sore S, Bako E, Nikiema MEM, Barro N, Bonkoungou IJO.   +9 more
europepmc   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

National surveillance of antimicrobial resistance in Iran using IAMR software: A hospital-based study. [PDF]

New Microbes New Infect
Hoseinzadeh E, Masoumi-Asl H.
europepmc   +1 more source

Nutritional Composition of African Catfish (Clarias gariepinus) in Ghana: Effects of Culture Conditions, Feed and Processing

Aquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
This review synthesizes current evidence on the nutritional composition of African catfish (Clarias gariepinus), with emphasis on Ghanaian aquaculture. The species is a valuable source of high‐quality protein, essential amino acids, minerals and vitamins, although lipid composition varies widely.
Amy Atter, Naomi Taye, Crossby Osei Tutu, Bernard Kwabena Asiedu, Reuben Acheampong, Hayford Ofori, Stephen Nketia, Richard Yaw Otwey, Christopher Galley, Frank Peget, Jackline Boateng, Patricia Mensah, Stacy Ayitey, Eric Dogbey, Seth Agyakwah, Wisdom Amoa‐Awua   +15 more
wiley   +1 more source

Gut microbiota reconstruction after liver transplantation and its association with early postoperative infections in patients with liver failure. [PDF]

Front Cell Infect Microbiol
Chen B, Chen J, Feng Z, Lv H, Lin Q, Jiang G.   +5 more
europepmc   +1 more source