Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli +5 more
wiley +1 more source
Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham +11 more
wiley +2 more sources
Emergence of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae with Penicillin-Binding Protein 3 Insertions, Taiwan, 2021. [PDF]
Long T +6 more
europepmc +1 more source
Cleaning Methods and Microbial Safety of Child Feeding Equipment: A Systematic Review
ABSTRACT Microbial contamination of child feeding equipment (CFE) includes feeding bottles, teats, and breast pumps. This contamination is a recognized pathway for enteric pathogen exposure during early childhood, particularly during the complementary feeding period (6–24 months).
Rehnuma Haque +7 more
wiley +1 more source
ABSTRACT Background Central venous catheters are essential in paediatric intensive care but are associated with catheter‐related bloodstream infections (CRBSIs) and skin complications. Chlorhexidine gluconate (CHG)‐impregnated dressings may reduce infection risk; however, concerns remain regarding their dermatological safety in vulnerable paediatric ...
Francisco Javier Portero‐Prados +2 more
wiley +1 more source
Critical Care Management Considerations in <i>Klebsiella pneumoniae</i> Invasive Liver Abscess Syndrome: Case Reports and Narrative Review. [PDF]
Chen J +4 more
europepmc +1 more source
Bacterial distribution and drug resistance patterns of urinary tract infection in tuberculosis patients: a 5-year retrospective study. [PDF]
Shui J, Tan A, Pan J, Shi G.
europepmc +1 more source
Antibacterial Activity of Heteropolytungstates Against Proteus mirabilis
We investigated the in vitro antibacterial activity of several heteropolytungstates against P. mirabilis, a drug‐resistant pathogen. All tested polyanions inhibited bacterial growth, with the Preyssler–Pope–Jeannin polyanion P5W30 exhibiting the highest activity (MIC = 0.78 mg/mL).
Nour El Ghouch +5 more
wiley +1 more source
Correction: Characteristics of the resistome and the potential for bloodstream infections in patients with gut colonization by <i>Klebsiella pneumoniae</i> undergoing hematopoietic stem cell transplantation. [PDF]
Qiu J, Zhuang Z, Zhu R, Cao Y, Xu X.
europepmc +1 more source
Optimisation of a Novel Class of DNA Gyrase Inhibitors to Improve Antibacterial Activity
This article describes efforts to increase the antibacterial activity of a recently reported class of novel DNA gyrase inhibitors known as the isoquinoline sulphonamides by improving their uptake in bacterial cells. As antibiotic resistance continues to rise, the need for new antibacterials is clear.
Meg I. Ferguson +9 more
wiley +1 more source

