Results 101 to 110 of about 270,953 (191)

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Nuclear receptor 4A1 is critical for neutrophil-dependent pulmonary immunity to Klebsiella pneumoniae infection

open access: yesFrontiers in Immunology
IntroductionBacterial pneumonia is a burdensome, costly disease and increasingly challenging to treat due to antibiotic resistance. Complex host-pathogen interactions regulate protective immunity.
Norie Sugitani   +10 more
doaj   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang   +4 more
wiley   +1 more source

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu   +7 more
wiley   +1 more source

A Fatal Case of Necrotizing Pneumonia Caused by Hypermucoviscous Klebsiella pneumoniae

open access: yesClinical Case Reports
Necrotizing pneumonia has a high mortality rate of approximately 50%. Its computed tomography findings lack enhancement in areas of consolidation. These findings should be interpreted as potentially indicative of a severe clinical course. Hypermucovisous
Kaori Ishiyama   +3 more
doaj   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

open access: yesEuropean Journal of Haematology, Volume 117, Issue 4, Page 1061-1071, October 2026.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen   +7 more
wiley   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

open access: yesAngewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber   +4 more
wiley   +1 more source

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