Results 91 to 100 of about 403,867 (337)

Estimating the number of infections caused by antibiotic-resistant Escherichia coli and Klebsiella pneumoniae in 2014: a modelling study [PDF]

, 2018
Background: The number of infections caused by resistant organisms is largely unknown. We estimated the number of infections worldwide that are caused by the WHO priority pathogens third-generation cephalosporin-resistant and carbapenem-resistant ...
Almagor, Jonatan, Carmeli, Yehuda, Fallach, Noga, Gladstone, Beryl Primrose, Tacconelli, Evelina, Temkin, Elizabeth   +5 more
core   +1 more source

Discrimination between Carbapenem-Resistant and Carbapenem-Sensitive Klebsiella pneumoniae Strains through Computational Analysis of Surface-Enhanced Raman Spectra: a Pilot Study

Microbiology spectrum, 2022
With the low-cost, label-free, and nondestructive features, Raman spectroscopy is becoming an attractive technique with great potential to discriminate bacterial infections.
W. Liu, Jia-Wei Tang, Jingqiao Lyu, Jun-Jiao Wang, Ya-Cheng Pan, Xinyi Shi, Qing-hua Liu, Xiao Zhang, B. Gu, Liang Wang   +9 more
semanticscholar   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Evolution of Antimicrobial Resistance in Klebsiella pneumoniae over 3 Years (2019–2021) in a Tertiary Hospital in Bucharest, Romania

Antibiotics
Background: The antimicrobial resistance (AMR) of Klebsiella pneumoniae recorded a steep upward trend over the last two decades, among which carbapenem-resistant Klebsiella pneumoniae (CRKP) is one of the most concerning strains considering the ...
Alexandra Cireșă, Daniela Tălăpan, Carmen-Cristina Vasile, Cristina Popescu, Gabriel-Adrian Popescu   +4 more
doaj   +1 more source

Outer Membrane Vesicles Derived from Klebsiella pneumoniae Are a Driving Force for Horizontal Gene Transfer

bioRxiv, 2021
Gram-negative bacteria release outer membrane vesicles (OMVs) into the extracellular environment. Recent studies recognized these vesicles as vectors to horizontal gene transfer, however the parameters that mediate OMVs transfer within bacterial ...
Federica Dell’Annunziata, C. Dell’Aversana, N. Doti, G. Donadio, F. Dal Piaz, Viviana Izzo, A. De Filippis, M. Galdiero, L. Altucci, G. Boccia, M. Galdiero, V. Folliero, G. Franci   +12 more
semanticscholar   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Detection Of clbB and clbN Genes in Isolated Klebsiella Pneumoniae of Biopsies from Colorectal Cancer Patient in Erbil Province

Eurasian Journal of Science and Engineering, 2023
Recently, it has been proved that some of Enterobacteriaceae like Klebsiella pneumoniae, which carry polyketide synthase (PKS) islands, damage human dsDNA by encoding Colibactin genotoxin; and finally, they induce some apoptosis in damaged mucosal cells.
Jutiyar Ibrahim, Hêro Farhad Salah
doaj   +1 more source

Imipenem resistance in clinical Escherichia coli from Qom, Iran [PDF]

, 2018
OBJECTIVE: The emergence of metallo-\u3b2-lactamase-producing Enterobacteriaceae is a worldwide health concern. In this study, the first evaluation of MBL genes, bla IMP and bla VIM , in Escherichia coli resistant to imipenem isolated from urine and ...
Esmkhani, M., Hashemi, A., Kermani, S., Piccirillo, A., Shams, E., Shams, S.   +5 more
core   +1 more source

Modelling the Gastrointestinal Carriage of Klebsiella pneumoniae Infections

bioRxiv, 2022
Klebsiella pneumoniae is one of the pathogens that is sweeping the world in the antibiotic resistance pandemic. Klebsiella colonizes the nasopharynx and the gut of healthy subjects in an asymptomatic manner, making gut colonization a requisite for ...
R. Calderón-Gonzalez, Alix Lee, G. López-Campos, Steven J. Hancock, Joana Sá-Pessoa, A. Dumigan, R. McMullan, Eric L Campbell, J. Bengoechea   +8 more
semanticscholar   +1 more source

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source