Results 81 to 90 of about 403,867 (337)

Mobilization of the nonconjugative virulence plasmid from hypervirulent Klebsiella pneumoniae

Genome Medicine, 2021
Background Klebsiella pneumoniae , as a global priority pathogen, is well known for its capability of acquiring mobile genetic elements that carry resistance and/or virulence genes.
Yanping Xu, Jianfeng Zhang, Meng Wang, Meng Liu, Guitian Liu, H. Qu, Jialin Liu, Z. Deng, Jingyong Sun, Hong-Yu Ou, J. Qu   +10 more
semanticscholar   +1 more source

Massive Increase, Spread, and Exchange of Extended Spectrum {beta}-Lactamase-Encoding Genes Among Intestinal Enterobacteriaceae in Hospitalized Children With Severe Acute Malnutrition in Niger. [PDF]

, 2011
Background. From the time of CTX-M emergence, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E) have spread worldwide in community settings as well as in hospitals, particularly in developing countries.
Andremont, A, Angebault, C, Armand-Lefèvre, L, Barbier, F, de Rekeneire, N, El Mniai, A, Hugede, H-C, Jacquier, H, Janssens, A-C, Page, A-L, Raskine, L, Ruppé, E, Sayadi, S, Woerther, P-L   +13 more
core   +2 more sources

Klebsiella pneumoniae capsular polysaccharide: Mechanism in regulation of synthesis, virulence, and pathogenicity

Virulence
Hypervirulent Klebsiella pneumoniae exhibits strong pathogenicity and can cause severe invasive infections but is historically recognized as antibiotic-susceptible. In recent years, the escalating global prevalence of antibiotic-resistant hypervirulent K.
Li Xu, Jiayang Li, Wenqi Wu, Xiuwen Wu, Jianan Ren   +4 more
semanticscholar   +1 more source

Finding Order in the Chaos: Outstanding Questions in Klebsiella pneumoniae Pathogenesis

Infection and Immunity, 2021
Klebsiella pneumoniae are Gram-negative facultative anaerobes that are found within host-associated commensal microbiomes, but they can also cause a wide range of infections that are often difficult to treat.
S. Gonzalez-Ferrer, H. Peñaloza, James A. Budnick, W. Bain, Hayley Nordstrom, Janet S. Lee, D. Van Tyne   +6 more
semanticscholar   +1 more source

Perbandingan Jumlah Koloni Bakteri Klebsiella Pneumoniae Pada Media Eosin Methylene Blue (Emb) Dan Media Endo Agar Plate (Eap) [PDF]

, 2019
Background: Klebsiella pneumoniae is a normal flora bacteria which commonly found on tractus digestivus. The laboratory measurement can be conducted by calculating the number of germ or bacteria which is inoculated on Eosin Methylene Blue and Endo Agar ...
Putri, Dwi Annisa
core  

Vaccine value profile for Klebsiella pneumoniae.

Vaccine
Klebsiella pneumoniae causes community- and healthcare-associated infections in children and adults. Globally in 2019, an estimated 1.27 million (95% Uncertainty Interval [UI]: 0.91-1.71) and 4.95 million (95% UI: 3.62-6.57) deaths were attributed to and
Z. Dangor, N. Benson, James A. Berkley, J. Bielicki, Merijn W Bijsma, Jonathan Broad, Ed T. Buurman, Alan S Cross, Erin M Duffy, K. E. Holt, P. Iroh Tam, M. Jit, Konstantinos Karampatsas, Michael Katwere, G. Kwatra, Ramanan Laxminarayan, K. Le Doare, Robert Mboizi, F. Micoli, C. E. Moore, Eve Nakabembe, Nichola R Naylor, Seamus O’Brien, C. Olwagen, D. Reddy, Charlene Rodrigues, David A. Rosen, M. Sadarangani, P. Srikantiah, S. Tennant, M. Hasso-Agopsowicz, S. Madhi   +31 more
semanticscholar   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Atividade in vitro de Gengibre e Açafrão contra Streptococcus pneumoniae e Klebsiella pneumoniae

RevSALUS
Introdução: Streptococcus pneumoniae e Klebsiella pneumoniae são causas principais de pneumonias associadas à morbi-mortalidade em crianças menores de 5 anos no mundo, representando 43% dos casos.
Eurico Paulo Airone, Maricela Tamayo, Graciano Cumaquela   +2 more
doaj   +1 more source

Klebsiella pneumoniae necrotizing fasciitis [PDF]

QJM, 2016
A 75-year-old male with history of diabetes mellitus presented to emergency room with fever and left wrist pain, erythema and swelling for three days. Physical exam revealed tensile skin with purplish discoloration and crepitus over left hand and wrist (Figure 1a). Swelling and extreme tenderness extended to left wrist and forearm.
T-T, Yang, Y-C, Chen
openaire   +2 more sources

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source