Results 81 to 90 of about 226,488 (310)

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

A Case of Multidrug-Resistant Klebsiella pneumoniae Treated with Carrimycin

, 2023
Wenjun Zhu,* Yaping Tian,* Lin Xiang, Linna Cao, Lirong He Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China*These authors contributed ...
Cao L, Tian Y, Zhu W, He L, Xiang L
core  

Antibiotic Resistance Pattern of Multi-drug Resistant Klebsiella pneumoniae and Detection of Carbapenem-resistance Genes [PDF]

Journal of Krishna Institute of Medical Sciences University, 2020
Background: Resistance to carbapenem is increasing over the years, which comes as one of the therapy of last resort therapy for critically ill patients. The current scenario is such that the antibiotics in hand are few for carbapenem-resistant Klebsiella
Shreya Shenoy , Suchitra Shenoy, Pooja Rao , Shrikala Baliga   +3 more
doaj  

Valorization of Textile Waste: Enzymatic Upcycling of Terephthalic Acid Toward a Sustainable PET Value Chain

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT The rapid expansion of the global textile industry, driven by the fast‐fashion paradigm, which is characterized by low‐cost, short‐lived garments made from inexpensive synthetic fibers, has intensified environmental pressures through increased waste generation, resource depletion, microplastic pollution, and greenhouse gas emissions ...
Fares Al‐Ostoot, Loredano Pollegioni, Elena Rosini   +2 more
wiley   +1 more source

Treatment of liver abscess caused by Klebsiella pneumoniae with multi-site infection: a case report

Journal of Medical Case Reports
Background Pyogenic liver abscesses are a fatal condition often seen in emergency departments. The major clinical presentations include weakness, anorexia, fever, chills, ventosity and abdominal pain.
Yong-gang Gui, Song-tao Shou, Yi Jiang, Qiu-ling Wang   +3 more
doaj   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

Genomic dataset of multidrug-resistant Klebsiella quasipneumoniae from Indonesia

BMC Research Notes
Objectives Klebsiella pneumoniae is a free-living bacterium found anywhere, including soil, water, and various types of plants, animals, and humans.
Nastiti Intan Permata Sari, Putu Yuliandari, Ajeng Kusumaningtyas Pramono, Dwi Tyastuti, Abdul Hadi Furqoni, Fitriana Fitriana, Sunarno Sunarno, Dewi Setyowati, Ni Luh Putu Indi Dharmayanti   +8 more
doaj   +1 more source

Chronic Klebsiella pneumonia: a rare manifestation of Klebsiella pneumonia.

Journal of thoracic disease, 2015
K. pneumoniae can present as two forms of community-acquired pneumonia, acute and chronic. Although acute pneumonia may turn into necrotizing pneumonia, which results in a prolonged clinical course, it often has a rapidly progressive clinical course. In contrast, chronic Klebsiella pneumonia runs a protracted indolent course that mimics other chronic ...
Viboon, Boonsarngsuk, Poungrat, Thungtitigul, Thitiporn, Suwatanapongched   +2 more
openaire   +1 more source

Cefepime exposure in prolonged or intermittent infusion in critically ill children

British Journal of Clinical Pharmacology, EarlyView.
Aims Cefepime is commonly used in critically ill children for whom there is a high between‐subject variability. To reach the therapeutic pharmacokinetic (PK) target in critically ill patients, prolonged infusion of beta‐lactams seems to be the most efficient.
Marc Hobeika, Deborah Hirt, Emmanuelle Bille, Sihem Benaboud, Julie Toubiana, Pierre‐Louis Léger, Jérôme Rambaud, Agathe Béranger, Delphine Callot, Sylvain Renolleau, Jean‐Marc Treluyer, Mehdi Oualha, Noémie de Cacqueray   +12 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source