Results 271 to 280 of about 228,400 (340)

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Intermediates in the conversion of 5′-S-methylthioadenosine to methionine in Klebsiella pneumoniae.

, 1988
Eric S. Furfine, Robert H. Abeles
openalex   +1 more source

SGLT2 Inhibitors and Complicated Urinary Tract Infections: A Rare Case of Emphysematous Pyelonephritis and Subsequent Recurrence Associated With Dapagliflozin Use

Clinical Case Reports, Volume 13, Issue 10, October 2025.
CT scan of abdomen and pelvis demonstrating left renal pelvis calculus and parenychemal gas involving the posterior interpolar region, consistent with emphysematous pyelonephritis. ABSTRACT Clinicians should exercise caution when prescribing dapagliflozin, a sodium‐glucose co‐transporter‐2 (SGLT2) inhibitor, as it may increase the risk of severe and ...
Harveen Kaur, Shaylika Chauhan, Manajyoti Yadav   +2 more
wiley   +1 more source

Discrimination of Klebsiella pneumoniae and Klebsiella quasipneumoniae by MALDI-TOF Mass Spectrometry Coupled With Machine Learning. [PDF]

Microbiologyopen
Nishikawa M, Tang W, Kostrzewa M, Rodgus J, Davies F, Liu Y, Jauneikaite E, Larrouy-Maumus G.   +7 more
europepmc   +1 more source

CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang, Qianqian Wang, Jiaming Zhang, Bingyu Li, Yuke Li, Zhengbo Chen, Dandan Guo, Shuying Feng   +7 more
wiley   +1 more source

Drug resistant Klebsiella pneumoniae from patients and hospital effluent: a correlation? [PDF]

BMC Microbiol
Masalane NS, Bester LA, Ismail A, Essack SY, Mbanga J.   +4 more
europepmc   +1 more source

Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor

, 1989
Xavier Nassif, J M Fournier, Josette Arondel, Philippe Sansonetti   +3 more
openalex   +1 more source

Nanostructured Biosensor Based on Multiwalled Carbon Nanotubes and Antimicrobial Peptide Temporin‐PTA for Bacterial Detection

Electroanalysis, Volume 37, Issue 10, October 2025.
A nanostructured electrochemical biosensor was developed by assembling MWCNTs with the antimicrobial peptide Temporin‐PTA. The platform enables rapid bacterial detection within 5 min, differentiates Gram‐negative from Gram‐positive pathogens, and achieves a low detection limit of 10 CFU/mL.
Antônio Oscar Gomes Filho, Alberto Galdino da Silva Júnior, Reginaldo G. Lima‐Neto, Ludovico Migliolo, Maria Danielly Lima de Oliveira, César Augusto Souza de Andrade   +5 more
wiley   +1 more source

Heteroresistance is associated with mutations during low concentration of tigecycline therapy in multiple-resistant Klebsiella pneumoniae. [PDF]

Ann Clin Microbiol Antimicrob
Zhang Q, Zheng L, Wen L, Li S, Nie Y, Chen J.   +5 more
europepmc   +1 more source