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Kleine-Levin Syndrome

Sleep Medicine Clinics, 2011
Kleine-Levin syndrome is a rare recurrent encephalopathy primarily affecting teenagers, characterized by relapsing-remitting episodes of hypersomnia along with cognitive, psychiatric and behavioral disturbances. During episodes, patients suddenly present hypersomnia (with sleep lasting 15-21 h/d), cognitive impairment (major apathy, confusion, slowness,
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Kleine-levin Syndrome and encephalitis

The Indian Journal of Pediatrics, 2002
Kleine-Levin Syndrome is characterized by hypersomnolence, hyperphagia and sexual disinhibition. The article reported a case of 10-year-old boy with a two-week history of altered sensorium, irrelevant talks, markedly increasing appetite and tendency to sleep most of the times.
Sujata, Sethi, Subhash C, Bhargava
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Polysomnography in Kleine-Levin syndrome

Neurology, 2008
Cause and pathogenesis of the Kleine-Levin syndrome (KLS), a recurrent hypersomnia affecting mainly male adolescents, remain unknown, with only scant information on the sleep characteristics during episodes. We describe findings obtained with polysomnography (PSG) and Multiple Sleep Latency Test (MSLT) and correlation obtained between clinical and PSG ...
Yu-Shu, Huang   +2 more
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Posttraumatic Kleine–Levin syndrome

General Hospital Psychiatry, 2006
Kleine–Levin Syndrome (KLS) is a rare disorder which most commonly occurs in adolescent males [1]. However, cases of KLS in females and older adults have been reported [2–4]. The key episodic triad of the syndrome are hypersomnia, hyperphagia and hypersexuality.
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The Kleine-Levin syndrome: A review

Psychosomatics, 1982
Abstract Because of its rarity, the Kleine-Levin syndrome may go unrecognized or be misdiagnosed. Primarily affecting male adolescents, it is characterized by periodic hypersomnia, excessive eating, and psychiatric symptoms ranging from lethargy to hallucinations. This article reviews the manifestations, diagnosis, and treatment of the disorder, with
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The Kleine-Levin syndrome

Journal of Pediatric Neurology, 2015
Why write an editorial on a rare and enigmatic disorder, which is difficult to diagnose, lacks a definite laboratory test and is hardly mentioned in the classical text books i.e., 18 sentences in Bradley’s Neurology in Clinical Practice [1], and 15 words including the two stating the name of the syndrome in Menkes Textbook of Child Neurology [2].
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[Kleine-Levin syndrome].

Fortschritte der Neurologie-Psychiatrie, 1991
The Kleine-Levin syndrome is generally considered to be a benign functional disorder of hypothalamic structures. Its onset is usually in adolescence. The most characteristic symptoms are periodic hypersomnia, excessive eating, hypersexuality, irritability and apathy. Associated features are depressive and schizophrenic symptoms.
C, Wurthmann, E, Klieser
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Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the TRANK1 gene loci

Proceedings of the National Academy of Sciences of the United States of America, 2021
Andrea Goldstein   +2 more
exaly  

Kleine–Levin Syndrome

Sleep Medicine Clinics, 2012
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The Kleine‐Levin syndrome

Neurology, 1965
H, Garland, D, Sumner, P, Fourman
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