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Hyperphagia: Current concepts and future directions proceedings of the 2nd international conference on hyperphagia [PDF]
ObjectiveHyperphagia is a central feature of inherited disorders (e.g., Prader–Willi Syndrome) in which obesity is a primary phenotypic component. Hyperphagia may also contribute to obesity as observed in the general population, thus raising the potential importance of common underlying mechanisms and treatments.
Steven B, Heymsfield +28 more
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Understanding the Effects of Antipsychotics on Appetite Control
Antipsychotic drugs (APDs) represent a cornerstone in the treatment of schizophrenia and other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so-called extrapyramidal side effects, and they have gradually been ...
Sayani Mukherjee +9 more
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Translational Neuroscience Approaches to Hyperphagia [PDF]
### Introduction 1Food intake in humans and other mammals is a complex process, resulting from the integration of homeostatic systems that monitor energy stores with hedonic drive resulting from the behaviorally reinforcing properties of food ([Fig.
Mario, Perello +3 more
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Atypical depression in bipolar affective disorder: a clinical case study
Atypical depression (AtD) is contrasted with classical endogenous melancholic depression and is characterized by the presence of its uncharacteristic abnormalities, but the list of the latter varies from individual symptoms (increased appetite, weight ...
M. S. Verbitskaya +4 more
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Fecal microbiota transplantation in a rodent model of short bowel syndrome: A therapeutic approach?
Extensive intestinal resection leads to Short Bowel Syndrome (SBS), the main cause of chronic intestinal failure. Colon preservation is crucial for spontaneous adaptation, to improve absorption and reduce parenteral nutrition dependence. Fecal microbiota
Salma Fourati +23 more
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The transcripts for Bdnf (brain-derived neurotrophic factor), driven by different promoters, are expressed in different brain regions to control different body functions. Specific promoter(s) that regulates energy balance remain unclear.
Pengcheng Chu, Wei Guo, He You, Bai Lu
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Monogenic obesity is a severe, genetically determined disorder that affects up to 1/1000 newborns. Recent reports on potential new therapeutics and innovative clinical approaches have highlighted the need for early identification of individuals with rare
Robert Šket +12 more
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The spring is a critical period when polar bears (Ursus maritimus Phipps, 1774) are thought to have peak access to seals and acquire the majority of their annual energy requirements during a period of hyperphagia. Pagano et al. (Pagano A.M., Atkinson S.N.
Anthony M. Pagano +2 more
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Glucocorticoid-Induced Fatty Liver Disease
Leili Rahimi,1 Aman Rajpal,1,2 Faramarz Ismail-Beigi1,2 1Department of Medicine, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; 2Cleveland VA Medical Center, Cleveland, OH, USACorrespondence: Faramarz ...
Rahimi L, Rajpal A, Ismail-Beigi F
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INTRODUCTION:Prader-Willi syndrome (PWS) is a complex genetic condition characterized by hyperphagia, hypotonia, low muscle mass, excess body fat, developmental delays, intellectual disability, behavioral problems, and growth hormone deficiency.
Virginia Kimonis +4 more
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