Health state utilities associated with hyperphagia: Data for use in cost‐utility models [PDF]
Obesity Science & Practice, 2023 Objective Rare genetic diseases of obesity typically present with hyperphagia, a pathologic desire to consume food. Cost‐utility models assessing the value of treatments for these rare diseases will require health state utilities representing hyperphagia.
Timothy A. Howell +5 more
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Hyperphagia severity is underestimated in adults with Bardet-Biedl syndrome – a mixed-method cross-sectional study in the United Kingdom [PDF]
Frontiers in EndocrinologyIntroductionBardet-Biedl syndrome (BBS) is a rare genetic disease caused by primary ciliary dysfunction leading to retinal degeneration, rod–cone dystrophy, polydactyly, hyperphagia, early‐onset obesity, renal dysfunction, hypogonadism, and learning ...
Jean Mossman +5 more
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Hyperphagia in craniopharyngioma- a real-world study from the international hypothalamic-pituitary brain tumors patient registry [PDF]
Scientific ReportsWe previously showed that hyperphagia affects quality of life of craniopharyngioma (CP) survivors. Characteristics of hyperphagia are unknown. This study aimed to characterize and quantify hyperphagia in CP survivors with and without hypothalamic obesity
Nathalie Kayadjanian +3 more
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Efficacy and safety of semaglutide for obesity and hyperphagia in adults with Prader-Willi syndrome [PDF]
Frontiers in EndocrinologyContextPrader-Willi syndrome is a genetic neurodevelopmental disorder characterized by hyperphagia and early-onset obesity from hypothalamic dysfunction with endocrinopathies and learning disability.
Shahd Ahmed +3 more
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Ожирение и метаболизм, 2013 Since ancient times, mankind is faced with the problem of obesity, caused by mismatch between energy intake and energy use. In recent decades, both women and men are involved in obesity epidemic, the occurrence of which can be attributed to the increased
T O Yalochkina, E A Pigarova
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Quality of life improvements with setmelanotide treatment in acquired hypothalamic obesity: TRANSCEND trial interview results from US participants [PDF]
Frontiers in Behavioral NeuroscienceIntroductionAcquired hypothalamic obesity (HO), caused by hypothalamic injury, is characterized by hyperphagia (i.e., insatiable hunger and abnormal food-seeking behaviors), reduced energy expenditure, and accelerated and sustained weight gain, all of ...
Christian L. Roth +11 more
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Medication Trials for Hyperphagia and Food-Related Behaviors in Prader–Willi Syndrome
Diseases (Basel, Switzerland), 2015 Prader-Willi syndrome (PWS) is a neurodevelopmental disorder caused by the absence of paternally expressed, imprinted genes on chromosome 15q11-13. Individuals with PWS characteristically have poor feeding and lack of appetite in infancy, followed by the
Theresa Strong, Jennifer L Miller
exaly +3 more sources
Setmelanotide – from genes to targeted therapy in some rare forms of obesity [PDF]
Farmacja Polska, 2021 Obesity is a serious public health concern. It significantly affects an individual’s quality of life and is associated with an increased risk of developing other conditions, including diabetes, hypertension, and cardiovascular complications.
Dawid Frączkowski
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Frontiers in Nutrition, 2022 Fasting with varying intensities is used to treat obesity-related diseases. Re-feeding after fasting exhibits hyperphagia and often rebound weight gain. However, the mechanisms underlying the hyperphagia and rebound remain elusive. Here we show that 24 h
Lei Wang +14 more
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MDM Policy & Practice, 2021 Background. Prader-Willi syndrome (PWS) is a rare neurodevelopmental disorder causing quality of life impairments such as insatiable hunger (hyperphagia) and obesity.
Jui-Hua Tsai +3 more
doaj +1 more source