Results 1 to 10 of about 26,081 (268)

Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response. [PDF]

Rev Endocr Metab Disord
Hyperphagia is a hallmark of both congenital and acquired rare melanocortin-4 receptor (MC4R) pathway diseases. Currently, the medical community has no standard treatment guidelines or approach to establishing treatment benefit.
Argente J, Clément K, Duis J, Farooqi IS, Kühnen P, Miller JL, Roth CL, van den Akker E.   +7 more
europepmc   +3 more sources

Natural History of Hyperphagia in Patients with Pseudohypoparathyroidism. [PDF]

J Clin Med
Background/Objectives: Pseudohypoparathyroidism (PHP) is a group of genetic disorders characterized by end-organ resistance to multiple hormones, short stature, brachydactyly, subcutaneous ossifications, obesity, and developmental delays.
Tamaroff J, Shoemaker AH.
europepmc   +2 more sources

Barriers, Limitations, and Experiences with Clinical Trials-Treatment in Rare Diseases with Prader-Willi Syndrome as an Example. [PDF]

Genes (Basel)
Butler MG, Silvey S, van Bosse HJP.
europepmc   +1 more source

Recent developments in GPCR signalling in appetite regulation. [PDF]

Biosci Rep
Brittain HR, Gorvin CM.
europepmc   +1 more source

A proof-of-concept study of pitolisant for excessive daytime sleepiness in patients with Prader-Willi syndrome. [PDF]

J Clin Sleep Med
Revana A, Bhattacharjee R, Miller JL, Chidekel A, Khanna P, Ratnam S, Runyan G, Bauer E, Davis Rapchak K, Seiden D, Budur K, Dayno JM.   +11 more
europepmc   +1 more source

Treatment Priorities in Craniopharyngioma: Perspectives of Survivors and Caregivers. [PDF]

Biomedicines
Kayadjanian N, Hsu EA.
europepmc   +1 more source

Exploring cannabinoid receptor CB1 autophagy and the obesity phenotype of p62-deficient mice. [PDF]

Biochem Biophys Rep
Keller C, Rading S, Candur B, Bindila L, Loers G, Karsak M.   +5 more
europepmc   +1 more source

Central nervous system adaptation mechanism of obesity induced by high-fat high-sucrose diet: Differences in brain function between obese and obese resistant rats based on fMRI. [PDF]

Metabol Open
Fang Q, Zhao S, Lin Q, Zhu X, Zheng C, Wang Y, Lu T, Zhu L.   +7 more
europepmc   +1 more source

Case Report: Schaaf-Yang Syndrome Milder Phenotype Due to Potential Pathogenic Novel Missense Variant as an Unusual Cause of Obesity in a Pediatric Patient. [PDF]

Appl Clin Genet
Pastucha D, Aleksijevic D, Hyjanek J, Vesely O, Klaskova E, Kolarikova K, Vodicka R.   +6 more
europepmc   +1 more source

Fiber Intervention Study in Prader-Willi Syndrome: Insights into Metabolic and Microbiota Shifts.

J Clin Endocrinol Metab
Tan Q, Peng Y, Deehan EC, Vieira FT, Ho BWP, Afhami S, Wine E, Madsen KL, Field CJ, Pakseresht M, Ilkayeva O, Newgard CB, Walter J, Tun HM, Haqq AM.   +14 more
europepmc   +1 more source