PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding
Neuron, 2020 Summary Calorie-rich diets induce hyperphagia and promote obesity, although the underlying mechanisms remain poorly defined. We find that short-term high-fat-diet (HFD) feeding of mice activates prepronociceptin (PNOC)-expressing neurons in the arcuate ...
Alexander Jais +20 more
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Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia [PDF]
, 2023 Antipsychotic (AP) drugs are efficacious treatments for various psychiatric disorders, but excessive weight gain and subsequent development of metabolic disease remain serious side effects of their use.
Libster, Avraham +23 more
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A role for GLP-1 in treating hyperphagia and obesity.
Endocrinology, 2020 Obesity is a chronic recurring disease whose prevalence has almost tripled over the past 40 years. In individuals with obesity there is significant increased risk of morbidity and mortality, along with decreased quality of life.
H. Grill
semanticscholar +1 more source
Resource allocation, hyperphagia and compensatory growth [PDF]
, 2004 Organisms often shown enhanced growth during recovery from starvation, and can even overtake continuously fed conspecifics (overcompensation). In an earlier paper (Ecology 84, 2777-2787), we studied the relative role played by hyperphagia and resource ...
Gurney, W.S.C. +3 more
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Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Tanycytes are nutrient-sensing cells that line the third ventricle within the hypothalamus. The role of tanycytes in the regulation of food intake has not been documented.
M. Bolborea +4 more
semanticscholar +1 more source
Ventromedial hypothalamic lesions without hyperphagia [PDF]
, 1963 Radio-frequency current and electrolysis were used to place ventromedial hypothalamic lesions in rats. In general, the two types of lesions differed in their effects on weight gain, water intake, and emotionality.
Robert W. Reynolds
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Additional file 1 of Burden of hyperphagia and obesity in Bardet–Biedl syndrome: a multicountry survey [PDF]
, 2023 Additional file 1. Supplementary Methods: Additional Survey Questions on the Impacts of Hyperphagia and Obesity Due to BBS. Supplementary Table 1. Symptoms and Impact of Hyperphagia in Patients With Bardet-Biedl Syndrome Aged
Alexandra Greatsinger (9490690) +8 more
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Development and validation of the Pediatric-Youth Hyperphagia Assessment for Prader-Willi syndrome [PDF]
Epidemiology and Health, 2022 OBJECTIVES Hyperphagia is a highly stressful, life-threatening feature of Prader-Willi syndrome (PWS). It is important to assess this complex behavior accurately over time.
Sung Yoon Cho +14 more
doaj +1 more source
Hyperphagia change from baseline to the end of Open-Label Treatment Overall, High Dose and/or moderate to severe hyperphagia. [PDF]
, 2019 Hyperphagia change from baseline to the end of Open-Label Treatment Overall, High Dose and/or moderate to severe hyperphagia.
Virginia Kimonis (7418696) +4 more
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Kleine − Levin syndrome: An ayurvedic perspective
Indian Journal of Ayurveda and Integrative Medicine KLEU, 2022 Kleine − Levin syndrome (KLS), also known as sleeping beauty syndrome, is characterized by the classic triad of hypersomnia, hyperphagia, and hypersexuality. It is an intriguing and severe disease with no clear etiology or management.
Prasad Mamidi, Kshama Gupta
doaj +1 more source