Results 51 to 60 of about 26,081 (268)

Hyperinsulinemia is a probable trigger for weight gain and hyperphagia in individuals with Prader‐Willi syndrome

Obesity Science & Practice, 2023
Objective Prader‐Willi syndrome (PWS) is the most frequently diagnosed genetic cause of early childhood obesity. Individuals with PWS typically progress through 7 different nutritional phases during their lifetime. The main objective of this study was to
Frederick A. Kweh, Carlos R. Sulsona, Jennifer L. Miller, Daniel J. Driscoll   +3 more
doaj   +1 more source

A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity

bioRxiv, 2020
Hepatic lipid accumulation is a hallmark of type II diabetes (T2D) and associated with hyperinsulinemia, insulin resistance, and hyperphagia. Hepatic synthesis of GABA, catalyzed by GABA-transaminase (GABA-T), is upregulated in obese mice.
Caroline E. Geisler, Susma. Ghimire, Stephanie M Bruggink, Kendra E Miller, Savanna N. Weninger, J. Kronenfeld, J. Yoshino, S. Klein, F. Duca, B. Renquist   +9 more
semanticscholar   +1 more source

Mode of action of DCCR in hyperphagia. [PDF]

, 2019
Mode of action of DCCR in hyperphagia.
Virginia Kimonis (7418696), Marie Wencel (7418702), Neil M. Cowen (7418705), Abhilasha Surampalli (7418699), June-Anne Gold (6413294)   +4 more
core   +1 more source

Maternal High Fat Diet Programs Male Mice Offspring Hyperphagia and Obesity: Mechanism of Increased Appetite Neurons via Altered Neurogenic Factors and Nutrient Sensor AMPK

Nutrients, 2020
Maternal high-fat (HF) is associated with offspring hyperphagia and obesity. We hypothesized that maternal HF alters fetal neuroprogenitor cell (NPC) and hypothalamic arcuate nucleus (ARC) development with preferential differentiation of neurons towards ...
M. Desai, M. Ferrini, G. Han, K. Narwani, M. Ross   +4 more
semanticscholar   +1 more source

Successful naltrexone-bupropion treatment after several treatment failures in a patient with severe monogenic obesity

iScience, 2023
Summary: We describe the therapeutic journey of a 33-year-old patient with early-onset obesity (BMI 56.7 kg/m2) and hyperphagia due to a likely pathogenic heterozygous melanocortin-4 receptor (MC4R) gene variant.She was unsuccessfully treated with ...
Mila S. Welling, Mostafa Mohseni, Eline S. van der Valk, Johanna M. van Hagen, Jan Steven Burgerhart, Mieke M. van Haelst, Elisabeth F.C. van Rossum   +6 more
doaj   +1 more source

Hyperphagia, weight gain and neonatal drug withdrawal [PDF]

, 2002
Hyperphagia, a classical feature of neonatal drug withdrawal, has been reported not to lead to excessive weight gain, but this is contrary to our clinical experience.
Shephard, R, Greenough, A; id_orcid, Johnson, K, Gerada, C   +3 more
core   +1 more source

METABOLIC EFFECTS OF HYPERPHAGIA IN THE HYPOTHALAMIC-HYPERPHAGIC RAT [PDF]

, 1966
Metabolic effects of hyperphagia have been investigated in male rats in which hyperphagia was induced by bilateral, electrolytic lesions in the region of the ventromedial nuclei of the hypothalamus.
K. K. May, J. R. Beaton
core   +1 more source

Home range, mobility and hibernation of brown bears (Ursus arctos, Ursidae) in areas with supplementary feeding

Nature Conservation Research: Заповедная наука, 2020
Supplementary feeding, although a common practice, is seldom studied in terms of its effect on non-targeted species, such as the brown bear (Ursus arctos). We conducted a GPS-GSM telemetry study on nine individuals (out of about 100 supposedly inhabiting
Vladimir R. Todorov, Diana P. Zlatanova, Kalina V. Valchinkova   +2 more
doaj   +1 more source

Stress, Subordination, and Anomalies of Feeding Across the Tree of Life: Implications for Interpreting Human Eating Disorders

Frontiers in Psychology, 2021
Eating behaviors of animals living in naturalistic environments offer unique insights into several dysregulated eating patterns observed in humans. Social subordination is a known precipitant of hyperphagia and hypophagia in human beings, and examples of
B. Natterson-Horowitz, B. Natterson-Horowitz, Julia H. Cho   +2 more
doaj   +1 more source

Translational Neuroscience Approaches to Hyperphagia [PDF]

The Journal of Neuroscience, 2010
### Introduction 1Food intake in humans and other mammals is a complex process, resulting from the integration of homeostatic systems that monitor energy stores with hedonic drive resulting from the behaviorally reinforcing properties of food ([Fig.
Mario, Perello, Jen-Chieh, Chuang, Michael M, Scott, Michael, Lutter   +3 more
openaire   +2 more sources