Results 31 to 40 of about 26,081 (268)

Fasting inhibits excitatory synaptic input on paraventricular oxytocin neurons via neuropeptide Y and Y1 receptor, inducing rebound hyperphagia, and weight gain

Frontiers in Nutrition, 2022
Fasting with varying intensities is used to treat obesity-related diseases. Re-feeding after fasting exhibits hyperphagia and often rebound weight gain. However, the mechanisms underlying the hyperphagia and rebound remain elusive. Here we show that 24 h
Lei Wang, Lei Wang, Lei Wang, Lei Wang, Shigetomo Suyama, Shigetomo Suyama, Samantha A. Lee, Samantha A. Lee, Yoichi Ueta, Yutaka Seino, Geoffrey W. G. Sharp, Toshihiko Yada, Toshihiko Yada, Toshihiko Yada, Toshihiko Yada   +14 more
doaj   +1 more source

Liraglutide attenuates nicotine self-administration as well as nicotine seeking and hyperphagia during withdrawal in male and female rats

Psychopharmacology, 2023
Rationale Nicotine cessation is associated with increased consumption of highly palatable foods and body weight gain in most smokers. Concerns about body weight gain are a major barrier to maintaining long-term smoking abstinence, and current treatments ...
Herman, Hayes, A. McGovern, Ashare, Schmidt   +4 more
semanticscholar   +1 more source

Measuring Meaningful Benefit-Risk Tradeoffs to Promote Patient-Focused Drug Development in Prader-Willi Syndrome: A Discrete-Choice Experiment

MDM Policy & Practice, 2021
Background. Prader-Willi syndrome (PWS) is a rare neurodevelopmental disorder causing quality of life impairments such as insatiable hunger (hyperphagia) and obesity.
Jui-Hua Tsai, Norah L. Crossnohere, Theresa Strong, John F. P. Bridges   +3 more
doaj   +1 more source

Hyperphagia in Prader-Willi syndrome with obesity: From development to pharmacological treatment.

Intractable & Rare Diseases Research, 2023
Prader-Willi syndrome (PWS) is a rare genetic disorder due to lack of genes expression inherited from the paternal chromosome 15q11-q13 region usually from paternal deletions, maternal uniparental disomy 15 or imprinting defect.
Qaddra Fahada Ab. Rahman, N. Jufri, A. Hamid   +2 more
semanticscholar   +1 more source

Measuring hyperphagia in patients with monogenic and syndromic obesity.

Appetite, 2022
BACKGROUND Hyperphagia is a key symptom in patients with monogenic obesity, but the assessment is challenging. OBJECTIVES We aimed to investigate the applicability of Dykens' Hyperphagia Questionnaire in patients with monogenic and syndromic obesity to
S. Zorn, J. von Schnurbein, M. Schirmer, S. Brandt, M. Wabitsch   +4 more
semanticscholar   +1 more source

Stress-induced hyperphagia: empirical characterization of stress-overeaters

BMC Public Health, 2022
Background Stressful situations can have an impact on an individual’s eating behavior. People vulnerable to the influence of stress tend to change the quantity and quality of their food intake.
B. Kaiser, Kathrin Gemesi, S. L. Holzmann, Monika Wintergerst, Martin Lurz, Hans Hauner, Georg Groh, M. Böhm, H. Krcmar, C. Holzapfel, K. Gedrich   +10 more
semanticscholar   +1 more source

Characteristics and relationship between hyperphagia, anxiety, behavioral challenges and caregiver burden in Prader-Willi syndrome

PLoS ONE, 2021
Objectives Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by maladaptive behaviors, amongst which hyperphagia is a life-long concern for individuals with PWS and their caregivers.
N. Kayadjanian, Caroline J Vrana-Diaz, Jessica E Bohonowych, T. Strong, Josée Morin, D. Potvin, L. Schwartz   +6 more
semanticscholar   +1 more source

A Cross-Sectional Study of Evening Hyperphagia and Nocturnal Ingestion: Core Constituents of Night Eating Syndrome with Different Background Factors

Nutrients, 2021
This web-based cross-sectional survey aimed to elucidate the differences between the two core symptoms of night eating syndrome (NES): evening hyperphagia and nocturnal ingestion in the general Japanese population aged 16–79 years.
Kentaro Matsui, Y. Komada, I. Okajima, Y. Takaesu, K. Kuriyama, Y. Inoue   +5 more
semanticscholar   +1 more source

Hyperphagia in intestinal disease [PDF]

Gut, 1974
Six patients with hyperphagia (ingestion of 5-11 000 Kcals/day) associated with severe malabsorption and steatorrhoea are described. The cause of the malabsorption was coeliac disease in three patients, Crohn's disease with ileal resection in two, and carcinoma of the pancreas in one patient.
R J, Hall, B, Creamer
openaire   +2 more sources

The consequences of hyperphagia in people with Prader-Willi Syndrome: A systematic review of studies of morbidity and mortality.

European Journal of Medical Genetics, 2021
Prader-Willi Syndrome (PWS) is a multi-system genetically determined neurodevelopmental disorder and the commonest cause of syndromal obesity. The development of hyperphagia in early childhood is part of the phenotype arising as a result of an impaired ...
S. Bellis, I. Kuhn, S. Adams, L. Mullarkey, A. Holland   +4 more
semanticscholar   +1 more source