Pituitary adenylate cyclase-activating polypeptide modulates circadian feeding and emotional behavior in mice independent of stress-induced hyperphagia [PDF]
Veterinary WorldBackground and Aim: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide widely implicated in stress responses, appetite regulation, and emotional behavior.
Ha Thi Thanh Nguyen +3 more
doaj +2 more sources
The study of hyperphagia in dementia [PDF]
, 1995 About 750 000 people suffer from dementia in the United Kingdom. This number is rising as the proportion of those over 65 years old increases. Excessive eating (hyperphagia) occurs at some stage in about 25 % of people suffering from dementia. This can lead to consumption of unsuitable substances and a significant gain in weight, which may make care at
Keene, J, Keene, Janet
core +6 more sources
Food responsiveness, addiction, and hyperphagia in Prader-Willi syndrome: a cross-sectional study of 210 Chinese patients [PDF]
Frontiers in EndocrinologyObjectivePrader–Willi syndrome (PWS) is the most common genetic syndromic obesity, characterized primarily by hyperphagia. It was described as excessive appetite, defective satiety, and obsession with food.
Chen-Xi Hu +7 more
doaj +2 more sources
Ghrelin Causes Hyperphagia and Obesity in Rats [PDF]
Diabetes, 2001 Ghrelin, a circulating growth hormone–releasing peptide derived from the stomach, stimulates food intake. The lowest systemically effective orexigenic dose of ghrelin was investigated and the resulting plasma ghrelin concentration was compared with that during fasting.
Wren, AM +10 more
openaire +4 more sources
Virus-Induced Voracity: Uncovering Hyperphagia Post-Herpes Simplex Virus Type 1 [PDF]
Case Reports in NeurologyIntroduction: Herpes simplex virus type 1 (HSV-1) is the leading cause of sporadic fatal encephalitis, typically presenting with temporal lobe abnormalities.
Arpan Mitra +5 more
doaj +3 more sources
Loss of Drosophila UBE3A phenocopies Piezo dysfunction and drives hyperphagic feeding in Drosophila [PDF]
FlyAngelman syndrome (AS) is a rare neurogenetic disorder characterized by developmental delay, speech impairment, ataxia, epilepsy, and in some cases hyperphagic feeding behavior.
Benjamin Geier +3 more
doaj +2 more sources
Chronic subordination stress induces hyperphagia and disrupts eating behavior in mice modeling binge-eating-like disorder [PDF]
Frontiers in Nutrition, 2015 Background Eating disorders are associated with physical morbidity and appear to have causal factors like stressful life events and negative affect. Binge eating disorder (BED) is characterized by eating in a discrete period of time a larger than normal ...
M. Razzoli, V. Sanghez, A. Bartolomucci
semanticscholar +2 more sources
Setmelanotide – from genes to targeted therapy in some rare forms of obesity [PDF]
Farmacja Polska, 2021 Obesity is a serious public health concern. It significantly affects an individual’s quality of life and is associated with an increased risk of developing other conditions, including diabetes, hypertension, and cardiovascular complications.
Dawid Frączkowski
doaj +1 more source
Hyperphagia in male melanocortin 4 receptor deficient mice promotes growth independently of growth hormone [PDF]
Journal of Physiology, 2016 Key points: Loss of function of the melanocortin 4 receptor (MC4R) results in hyperphagia, obesity and increased growth. Despite knowing that MC4Rs control food intake, we are yet to understand why defects in the function of the MC4R receptor contribute ...
H. Y. Tan +5 more
semanticscholar +2 more sources
Journal of Clinical Endocrinology and Metabolism, 2023 Context Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by endocrine and neuropsychiatric problems including hyperphagia, anxiousness, and distress.
E. Roof +36 more
semanticscholar +1 more source