Results 211 to 220 of about 61,743 (326)
Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes
Advanced Therapeutics, Volume 9, Issue 2, February 2026.Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava +9 more
wiley +1 more source
LncRNA MEG3 Induces Endothelial Differentiation of Adipose-derived Stem Cells by Targeting MiR-145-5p/KLF4 [PDF]
, 2022 Hailong Zhang +5 more
openalex +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
, 2017 Meera Murgai +12 more
openalex +2 more sources
Biotechnology and Bioengineering, Volume 123, Issue 2, Page 363-378, February 2026.The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes +4 more
wiley +1 more source
KLF4 promotes podocyte differentiation [PDF]
Nature Reviews Nephrology, 2014 openaire +1 more source
Brain and Behavior, Volume 16, Issue 2, February 2026.Mechanism of rupture hemorrhage in cerebral cavernous malformations. Environmental and immune factors promote the progression of lesions and induce the risk of abnormal formation or rupture of cerebrovascular vessels. Abstract Purpose of Review To review how the immune microenvironment and oxidative stress modulate the initiation, maturation, and ...
Xuesai Zhu +3 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.Graphical highlights Tumour subpopulations with high malignancy show reduced interferon signalling and reduced MHC‐I expression. Tumour‐associated macrophages (TAMs) differentiate into two opposing states: SPP1+ TAMs and CXCL9+ TAMs. Among immune ecotypes, T‐cell‐enriched ecotypes are linked with high MHC‐I expression in tumour cells while desert ...
Lingjuan Huang +13 more
wiley +1 more source