Results 221 to 230 of about 54,134 (244)

Determining the role of klf4 in zebrafish development [PDF]

, 2023
The Krüppel-like factor (KLF) family of genes encode transcriptional regulatory proteins that play key roles in differentiation. Gene knockout studies of KLFs have shown essential roles in organogenesis. Although much is known about the biochemistry of interaction between the three C-terminal C2H2 zinc fingers and CACC or GC rich DNA sequences, very ...
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Secretory meningioma with KLF4 K409Q mutation in collision with glioma

Clinical Neuropathology, 2015
The simultaneous occurrence of two primary intracranial tumors is a rare event, especially if unrelated to radiotherapy or genetic disorders. We present two patients, both with two primary intracranial tumors simultaneously present at adjacent sites, in order to explore a possible mechanism of synchronous tumor formation.We performed a molecular ...
Juan, Ruiz, Elena, Capilla, Juan F, Díaz, Juan A, Ruiz, Jesus, Andrade, Teresa, Hernández, Manuela, Mollejo, Bárbara, Meléndez   +7 more
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KLF4 regulates the expression of interleukin-10 in RAW264.7 macrophages

Biochemical and Biophysical Research Communications, 2007
Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing transcription factor. In the current study, RAW264.7 murine macrophages were treated with Escherichia coli lipopolysaccharide (LPS) to determine the expression of KLF4.
Junwen, Liu, Huali, Zhang, Ying, Liu, Kangkai, Wang, Yansheng, Feng, Meidong, Liu, Xianzhong, Xiao   +6 more
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YY1 and KLF4: Their Role in Gastrointestinal Malignancies

2017
Gastrointestinal (GI) malignancies are among the most serious threats to global health and are among the major causes of morbidity and mortality. KLF4 and YY1 occupy a central niche and can influence the process of oncogenesis of the various tissues of the GI tract in a major way by being closely associated with several cellular processes such as cell ...
Himanshu Tillu, Ganji Purnachandra Nagaraju   +1 more
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Roles of Klf4 in embryonic stem cells

2015
Human and mouse ES cells are defined by their ability to confer self-renewal and differentiate into various cell types, making them an invaluable tool for investigation of Stem cell maintenance, differentiation, and reprogramming. Human ES cells have infinite potential for therapeutic applications.
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KLF4 in Ovarian Cancer

Forum on Immunopathological Diseases and Therapeutics, 2016
Junming Yue, Baojin Wang, Ziyun Du, Lawrence M. Pfeffer   +3 more
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USP11 degrades KLF4 via its deubiquitinase activity in liver diseases

Journal of Cellular and Molecular Medicine, 2021
Heeyoung Yang, Daeui Park, Tamina Park   +2 more
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KLF4 Regulates Abdominal Aortic Aneurysm Morphology and Deletion Attenuates Aneurysm Formation

Circulation, 2013
Morgan Salmon, William F Johnston, Andrew J Woo   +2 more
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KLF4

2018
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ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4

Cancer Letters, 2019
Hongyan Chen, Zhuan Zhou, Yong Wan
exaly